THE WELCH COMPANY
440 Davis Court #1602
San Francisco, CA 94111-2496
415 781 5700
rod@welchco.com


S U M M A R Y


DIARY: June 4, 2015 07:04 PM Thursday; Rod Welch

Blood tests lab reports expedited low cost Elizabeth Holmes with Theranos Company.

1...Summary/Objective


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CONTACTS 

SUBJECTS
Blood Tests New Microanalytic Process Low Cost Expedited Lab Results                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
0703 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
0703 -    ..
0704 - Summary/Objective                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
0705 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
070501 - Follow up ref SDS 1 0000.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
070502 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
070503 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
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070507 -  ..
0706 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
0707 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
0708 - Progress                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
0709 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
070901 - Elizabeth Holmes, Founder of Teranos Company, located in Palo Alto,                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
070902 - was interviewed by Charlie Rose today.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
070904 -  ..
070905 - The company provides a range of blood tests based on a small amount                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
070906 - of blood drawn with a pin prick, rather than a small tube of blood                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
070907 - drawn with traditional needle stick.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
070909 -  ..
070910 - Theranos Company on the Internet...                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
070911 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
070912 -              https://www.theranos.com/                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
070914 -  ..
070915 - Navigating through the services Theranos advertises cholesterol test                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
070916 - for about $3.00.  Not clear if this yields results on standard lipid                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
070917 - panel...                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
070918 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
070919 -                Cholesterol                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
070920 -                HDL                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
070921 -                Triglycerides                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
070922 -                LDL-C                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
070924 -  ..
070925 - Nothing is evident on NMR lipids for LDL-P.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
070927 -  ..
070928 - Theranos blood test kits are evidently available at Wallgreens in some                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
070929 - communities. ref SDS 0 XX4K                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
070930 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
070932 -  ..
070933 - Wikipedia describes Teranos...                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
070934 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
070935 -              http://en.wikipedia.org/wiki/Theranos#Litigation                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
070936 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
070937 -        Theranos is a privately held health-technology and                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
070938 -        medical-laboratory-services company based in Palo Alto,                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
070939 -        California that has developed novel approaches for laboratory                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
070940 -        diagnostic tests using blood.[2] The company's blood-testing                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
070941 -        platform uses a few drops of blood obtained via a finger-stick                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
070942 -        rather than vials of blood obtained via traditional                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
070943 -        venipuncture,[3] and utilizes microfluidics technology.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
070945 -         ..
070946 -        Theranos was founded in 2003 by Elizabeth Holmes with the goal                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
070947 -        of streamlining and standardizing blood tests by creating a                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
070948 -        hand-held device.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
070950 -         ..
070951 -        She had previously founded a software company and worked on a                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
070952 -        protein microarray for the detection of SARS in Singapore,[1]                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
070953 -        and left Stanford University at age 19 while a sophomore                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
070954 -        majoring in chemical engineering, to start Theranos with a                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
070955 -        bridge loan from a venture capitalist.[5] Holmes' Stanford                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
070956 -        chemical engineering professor Channing Robertson had                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
070957 -        encouraged her in the endeavor, and joined the board of                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
070958 -        directors.[1] The company had raised $16 million in two rounds                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
070959 -        of initial fundraising,[6] and $28.5 million in a third round                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
070960 -        in 2006.[7]                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
070962 -         ..
070963 -        In 2010, Theranos raised an additional $45 million from a                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
070964 -        single unnamed investor,[6] bringing its total funding to more                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
070965 -        than $70 million. Investors include Draper Fisher Jurvetson,                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
070966 -        ATA Ventures, Tako Ventures, Continental Properties Inc.,[8]                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
070967 -        and Larry Ellison, CEO of Oracle.[1]                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
070969 -         ..
070970 -        As described in general terms for a business periodical in                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
070971 -        2006, Theranos' device design uses a fingerstick to draw a                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
070972 -        microliter sample of blood into a disposable cartridge, which                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
070973 -        is loaded into a the device's "reader" for analysis; results                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
070974 -        are sent wirelessly from the reader to a secure database, from                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
070975 -        where they go online to the patient or patient's physician.[11]                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
070976 -        The company's device claims include that the results will be                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
070977 -        received faster than the usual three-day delay for centralized                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
070978 -        laboratory testing,[1] that up to 30 blood tests can be                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
070979 -        performed on a single sample,[25] and that its design will                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
070980 -        ensure accuracy by reducing or eliminating human handling and                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
070981 -        delays associated with traditional tests.[25]                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
070983 -         ..
070984 -        The company reports that tests are being performed at a                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
070985 -        CLIA-certified laboratory; as of January 2015 the documentation                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
070986 -        on each test includes analyte being detected, and the approved                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
070987 -        means of detection.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
070989 -         ..
070990 -        Theranos has begun to offer services directly to consumers via                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
070991 -        Theranos Wellness Centers located inside Walgreens stores                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
070992 -        (beginning in 2013),[26][27] with, as of January 2015, one                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
070993 -        posted location in Palo Alto, CA, and forty posted locations                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
070994 -        in Phoenix, AZ.[28] While reports have appeared that Theranos'                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
070995 -        blood tests mainly cost under $10, as of January 2014, prices                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
070996 -        had been posted for more than 235 available tests at                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
070997 -        Walgreens, Inc. (online, via outlink to the Theranos site),                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
070998 -        ranging in price from $1.55 to $117.96 (for an "Auto"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
070999 -        urinalysis and a genotypic test for Hepatitis C virus,                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
071000 -        respectively), with many in the range of $2 to $20, and                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
071001 -        typical panel prices being on the order of tens of dollars                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
071002 -        (e.g., with the combined tests of a standard Comprehensive                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
071004 -         ..
071005 -        metabolic panel of protein, electrolytes, sugar, cholesterol,                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
071006 -        and kidney and liver enzyme tests[29] accruing at                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
071007 -        Walgreens-Theranos to ~$45.)[30][31] (As noted, full                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
071008 -        information on each test is not available at the Walgreens or                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
071009 -        Theranos sites, as of January 2015.[32]) Based on its                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
071010 -        calculations regarding its pricing and test use by American                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
071011 -        consumers, the company has made claims that low-cost blood                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
071012 -        tests could save U.S.  Medicare and Medicaid, on average,                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
071013 -        around $20 billion per annum.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
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