THE WELCH COMPANY
440 Davis Court #1602
San Francisco, CA 94111-2496
415 781 5700
rod@welchco.com


S U M M A R Y


DIARY: October 28, 2014 08:38 PM Tuesday; Rod Welch

Labcorp and Liposcience notified error LDL-P conflicts TG/NMR ratio.

1...Summary/Objective
2...LDL-C 90 LDL-P 1586 HDL 57 Hike 200 Miles Weight Maintain 180


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CONTACTS 

SUBJECTS
CBC Lab WBC 12.8 Elevated Blister Big Toe Left Foot VA for Meeting D                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
2303 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
2303 -    ..
2304 - Summary/Objective                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
2305 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
230501 - Follow up ref SDS 75 0000. ref SDS 74 0000.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
230502 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
230503 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
230504 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
230506 -  ..
2306 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
2307 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
2308 - Background                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
2309 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
230901 - On 131016 1632 submit letter for agenda meeting to review lab results                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
230902 - scheduled 131017 1000. ref SDS 41 X45G                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
230904 -  ..
230905 - On 140131 0815 ordered another lab - cbc, electrolytes, lipid with NMR                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
230906 - - from Labcor to get LDL-P. ref SDS 50 X45G                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
230908 -  ..
230909 - On 140201 1159 had full lab with NMR lipid panel drawn at John Muir                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
230910 - Hospital on Treat, and by Labcorp. ref SDS 51 RP4N                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
230912 -  ..
230913 - On 140203 1147 had partial lab drawn at VA in Martinez. ref SDS 52                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
230914 - KK9M                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
230916 -  ..
230917 - On 140507 0857 ordered another full lab from Labcorp with NMR lipid                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
230918 - panel. ref SDS 58 OO5G                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
230920 -  ..
230921 - On 140508 1133 lab blood daw at Labcorp with John Muir Medical Center                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
230922 - on Treat Blvd in Concord. ref SDS 59 445G                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
230924 -  ..
230925 - On 140514 0950 VA partial lab at Medical Center in San Francisco.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
230926 - ref SDS 62 X45G                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
230928 -  ..
230929 - On 140814 1530 VA full lab at Clinic in Martinez. ref SDS 68 X45G                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
230931 -  ..
230932 - On 140827 1422 VA partial lab CBC only at Clinic in Martinez re-check                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
230933 - elevated WBC. ref SDS 72 X45G                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
230935 -  ..
230936 - On 141020 1025 Labcorp partial lab CBC Electrolytes Urinalysis, but                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
230937 - mistakenly omitted NMP lipid panel. ref SDS 73 X45G                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
230939 -  ..
230940 - On 141021 1009 Labcorp NMR Lipid panel, ref SDS 75 U45J, and                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
230941 - Homocyst(e)ine. ref SDS 75 CM6J                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
230942 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
230943 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
230944 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
230946 -  ..
2310 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
2311 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
2312 - Progress                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
2313 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
231301 - LDL-C 90 LDL-P 1586 HDL 57 Hike 200 Miles Weight Maintain 180                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
231302 - 
231303 - Follow up ref SDS 75 IM9N, ref SDS 74 IM9N.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
231304 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
231305 -        01  S7  Deanna Franke, PhD                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
231306 -                Liposcience Inc                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
231307 -                2500 Sumner Blvd, Raleigh, NC 27616-3235                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
231308 -                877 547 6837                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
231309 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
231310 -                customer.service@liposcience.com                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
231312 -  ..
231313 - Called Liposcience and talked to Brenda in Customer service.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
231315 -  ..
231316 - Explained possible error LDL-P conflicts with TG/HDL ratios reported                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
231317 - for Labcorp lab on 141021 1150. ref SDS 75 QV5G                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
231319 -  ..
231320 - Brenda advised questions can be submitted to Deanna Franke, PhD.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
231322 -  ..
231323 - Submitted letter saying...                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
231324 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
231325 -    1.  Subject:  LDL-P Conflicting Results Specimen 294-544-7457-0                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
231326 -        Date:  2014-10-28 21:11                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
231330 -         ..
231331 -    2.  Below is a letter from Health Testing Centers with attached                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
231332 -        Labcorp test results for...                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
231334 -         ..
231335 -    3.  Customer........................ Rod Welch                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
231336 -        Control ID...................... 16235437                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
231337 -        Acct #.......................... 09419602                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
231338 -        Specimen ID..................... 294-544-7457-0                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
231339 -        Date collected.................. 10/21/2014 1021 Local                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
231340 -        Date entered.................... 10/21/2014                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
231341 -        Date reported................... 10/23/2014 1314 ET                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
231343 -         ..
231344 -    4.  You can open Labcorp PDF file attached to HTC's letter.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
231346 -         ..
231347 -    5.  The lab included NMR LipoProfile performed by...                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
231349 -         ..
231350 -    6.  Deanna Franke, PhD                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
231351 -        Liposcience Inc                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
231352 -        2500 Sumner Blvd, Raleigh, NC 27616-3235                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
231353 -        877 547 6837                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
231355 -         ..
231356 -    7.  Talked to Brenda earlier today, and she suggested submitting                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
231357 -        questions to this address on following issues...                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
231359 -         ..
231360 -    8.  LDL-P 1586 seems conflicting with TG/HDL ratio 80/55 = 1.41,                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
231361 -        and further with lipid lab at VA an hour later reporting TG/HDL                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
231362 -        65/57 = 1.14.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
231364 -         ..
231365 -    9.  On prior lab 140508, Liposcience reported LDL-P 851 with TG/HDL                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
231366 -        ratio 59/67 = 0.88                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
231368 -         ..
231369 -   10.  And, on earlier lab 140203 you reported LDL-P 861 with TG/HDL                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
231370 -        ratio 68/61 = 1.11.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
231372 -         ..
231373 -   11.  Sources, including my medical team at VA/UCSF, maintain TG/HDL                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
231374 -        ratio should predict LDL-P.  If so, then TG/HDL correlation                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
231375 -        with LDL-P must be stable within a range in order to be                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
231376 -        reliable.  Seems like the numbers in this case indicate                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
231377 -        possible error reporting LDL-P 1586 higher than TG/HDL predicts                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
231378 -        from multiple sources.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
231380 -         ..
231381 -   12.  Please call to discuss, whether there might be an error in the                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
231382 -        lab this cycle, perhaps the specimen got corrupted somehow.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
231383 -        Can the specimen be retested?  Alternatively, I could do                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
231384 -        another blood draw at Labcorp.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
231386 -         ..
231387 -   13.  Your support is appreciated.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
231389 -         ..
231390 -   14.  Sincerely,                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
231392 -         ..
231393 -   15.  Rod                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
231394 -        925 849 4745                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
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