THE WELCH COMPANY
440 Davis Court #1602
San Francisco, CA 94111-2496
415 781 5700
rodwelch@pacbell.net


S U M M A R Y


DIARY: February 3, 2009 02:17 PM Tuesday; Rod Welch

Millie notifies medical team VCI can provide hyperthemia tomorrow in time
to be effective recoverying from IBC 6th relapse.

1...Summary/Objective


..............
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SUBJECTS
Default Null Subject Account for Blank Record

0403 -
0403 -    ..
0404 - Summary/Objective
0405 -
040501 - Follow up ref SDS 59 0000. ref SDS 57 0000.
040502 -
040503 -
040504 -
040505 -
040506 -
040508 -  ..
0406 -
0407 -
0408 - Progress
0409 -
040901 - Background...
040902 -
040903 -    1.  Case study dilemma balancing sunitinib treatments to optimize
040904 -        recovery from 5th relapse IBC, and without increasing
040905 -        debilitating side effects that prevent exercise required to
040906 -        benefit from recovery. ref SDS 10 I87N
040908 -         ..
040909 -    2.  On 090108 examination at UCSF showed possible progression of
040910 -        IBC in breastbone area, as set out in Millie's letter to the
040911 -        medical team on 090109. ref SDS 12 UC4H  Millie reported severe
040912 -        side effects shown by wide range of blood counts falling.
040913 -        ref SDS 12 UF3Q  Medical team prescribed another cycle
040914 -        sunitinib treatment, with cyclophosphamide paused until blood
040915 -        counts increase to a safe level. ref SDS 12 UF3T
040917 -         ..
040918 -    3.  On 090109 Millie's letter reports rise of IBC with sunitinib
040919 -        seen at UCSF on 090108 occurred previously, cited in Millie's
040920 -        letter on 081125, ref SDS 5 XX4P; there was rise of IBC and
040921 -        then substantial recovery reported again on 081217, ref SDS 6
040922 -        YJ4V; on 081230 Millie's letter reported on 081224 and 081225
040923 -        rise of IBC, and then improvement on 081226, ref SDS 10 JV5M;
040924 -        most recently on 090106 Millie cited again advance of IBC on
040925 -        081224 and 081225, and now disease seems to be subsiding again.
040926 -        ref SDS 11 YO4V]
040928 -         ..
040929 -    4.  On 090115 Millie letter to Catherine and Diane in the Infusion
040930 -        Clinic at UCSF reported rising side effects of sunitinib
040931 -        protocol, ref SDS 15 5J9Y; she tried hiking a few times, but
040932 -        this hurts her feet (peripheral neuropathy) and legs are very
040933 -        weak, shown in patient history on daily treatments. ref SDS 14
040934 -        KL4J  Have been spending more time in the gym doing aerobics,
040935 -        which is a little more tolerable. ref SDS 14 3E4K
040937 -         ..
040938 -    5.  On 090116 Glenna called to ask about response to treatment and
040939 -        side effects, ref SDS 16 JY6L, and was advised that IBC in the
040940 -        breastbone area was stable to worse, and other sites are stable
040941 -        to improved with sunitinib protocol, citing the record of
040942 -        patient history the day before on 090115. ref SDS 14 124N
040944 -         ..
040945 -    6.  On 090116 during call from Glenna advised that Millie wants to
040946 -        reduce the dose of sunitinib in order to reduce debilitating
040947 -        side effects, and requested remedy to reduce side effects with
040948 -        full dose of sunitinib in order to optimize recovery.
040949 -        ref SDS 16 JY7J
040951 -         ..
040952 -    7.  On 090116 Millie received a letter from Glenna transmitting a
040953 -        copy of a letter Glenna wrote to the doctor reporting
040954 -        understandings from telecon in the morning on 090116,
040955 -        ref SDS 18 YN9H; Glenna's letter to the doctor described
040956 -        difficulty tolerating side effects of sunitinib, ref SDS 18
040957 -        4P5M, that Millie wants to reduce the dose to reduce side
040958 -        effects, but is afraid about losing benefits of recovering
040959 -        from IBC. ref SDS 18 HV3M
040961 -         ..
040962 -    8.  On 090116 Glenna's letter to the doctor asked about changing to
040963 -        another treatment. ref SDS 18 HV3O
040965 -         ..
040966 -    9.  On 090116 Glenna planned to meet with the doctor later in the
040967 -        day on 090116 to discuss changing Millie's treatment.
040968 -        ref SDS 18 HP4J
040970 -         ..
040971 -   10.  On 090116 Millie's letter to the medical team clarifies telecon
040972 -        on condition following examination at UCSF on 090108, reporting
040973 -        IBC in breastbone area looks stable to worse, and everywhere
040974 -        else looks improved to stable, indicating recovery has slowed
040975 -        ref SDS 19 IS6G, relative to findings on 081218, ref SDS 7
040976 -        VD4F, confirmed in Millie's letter later that day reporting
040977 -        significant recovery. ref SDS 8 GF8V
040979 -         ..
040980 -   11.  On 090118 Millie talks about wanting to end treatment with
040981 -        sunitinib that seems now less effective and has severe side
040982 -        effects after adding cycloposphamide. ref SDS 20 UC41
040984 -         ..
040985 -   12.  On 090121 Millie letter to primary care physician says very
040986 -        pleased to take this occasion on my birthday to say thanks for
040987 -        such great care the past 7 years.  You noted in our first
040988 -        meeting on 020321 that Oncology presents unique challenges.
040989 -        ref SDS 1 R94H  My case has been complicated by other maladies
040990 -        that strain resources of time, money, and emotion.  Having you
040991 -        at the helm with Arlette's assistance has been a blessing.
040992 -        ref SDS 23 F23Y
040994 -         ..
040995 -   13.  On 090121 Glenna calls and asks again about Millie's response
040996 -        to treatment, ref SDS 24 AJ3J, following up her call on 090116,
040997 -        ref SDS 16 JY6L, and per background above. ref SDS 24 JY5I
040999 -         ..
041000 -   14.  On 090121 during call from Glenna reported patient history,
041001 -        ref SDS 24 ZO4F, on 090120 shows IBC rash looks improved to
041002 -        stable, and nodules in the breastbone area seem worse,
041003 -        ref SDS 22 124N, relative to detailed review on 090110,
041004 -        ref SDS 13 124N, and after 11 days of treatment with only
041005 -        sunitinib, and 25 total treatments with sunitinib, since the
041006 -        pause on 081218 and resuming on 081226. ref SDS 21 6C4J
041008 -         ..
041009 -   15.  On 090121 during call from Glenna reported patient history
041010 -        reported IBC worsening in breastbone area has progressed onto
041011 -        the right breast and spread toward the left chest reflects
041012 -        rising cancer marker, ref SDS 24 N95K, Labs at Kaiser on 090116
041013 -        report CA 15-3 303. ref SDS 17 PQTQ  This record indicates
041014 -        Millie has suffered 6th relapse of IBC.
041016 -         ..
041017 -   16.  On 090121 Glenna asked for most severe side effects from
041018 -        continuing with sunitinib treatment. ref SDS 24 TW53
041020 -         ..
041021 -   17.  On 090121 Glenna asked for Millie's records on Doctor Rugo's
041022 -        plans for follow on treatments?  During the call developed
041023 -        background on UCSF planning for Millie's future treatment after
041024 -        sunitinib. ref SDS 24 Y67L
041026 -         ..
041027 -   18.  On 090121 Glenna reported during the call that she would send
041028 -        another letter to Doctor Rugo explaining Millie's slow response
041029 -        to treatment with sunitinib, and supplementing Glenna's letter
041030 -        to the doctor on 090116, ref SDS 35 SY5J; Glenna further advised
041031 -        during the call on 090121 that she would meet again with Doctor
041032 -        Rugo to discuss plans for changing Millie's treatment to
041033 -        recover from Millie's 6th IBC relapse. ref SDS 24 N976
041035 -         ..
041036 -   19.  On 090121 patient history summarized to faciliate Glenna's
041037 -        meeting with Doctor to figure out Millie's next treatment.
041038 -        ref SDS 24 NU5H
041040 -             ..
041041 -        a.  Laboratory blood tests listed for Millie to facilitate UCSF
041042 -            considering Millie's next treatment. ref SDS 24 6Y9K
041044 -             ..
041045 -        b.  Image test history of PET, CT, Xray, MRI listed for Glenna
041046 -            to discuss with Doctor Rugo discussing Millie's next
041047 -            treatment. ref SDS 24 216F
041049 -             ..
041050 -        c.  Treatment history listed for Glenna to discuss with Doctor
041051 -            Rugo discussing Millie's next treatment. ref SDS 24 H16M
041053 -             ..
041054 -        d.  Strategy considerations for selecting Millie's next
041055 -            treatment. ref SDS 24 558O
041057 -         ..
041058 -   20.  On 090122 telephone message from Glenna reported that the
041059 -        doctor ended treament with sunitinib protocol; Glenna met with
041060 -        Doctor Rugo to develop treatment plan for Millie, and UCSF
041061 -        scheduled Millie to start new treatment on 090129. ref SDS 28
041062 -        K96F
041064 -         ..
041065 -   21.  On 090123 primary care physician at Kaiser cited sudden relapse
041066 -        of IBC with nodules spreading in the breastbone area, and
041067 -        cancer marker elevated to CA 15-3 303 in the labs at Kaiser on
041068 -        090116, ref SDS 17 PQTQ, shows Millie needs immediate change of
041069 -        treatment to prevent cancer from cascading out of control, and
041070 -        that UCSF should prescribe treatment, ref SDS 33 RK6O, because
041071 -        Millie's 6th relapse of IBC shows cancer has mutated to cells
041072 -        that are now very resistant to treatments available at Kaiser,
041073 -        as discussed previously during the meeting at Kaiser on 080829,
041074 -        and cited in Millie's letter to the medical team. ref SDS 4
041075 -        RP9R
041077 -         ..
041078 -   22.  On 090123 Millie's letter to medical team reports progress at
041079 -        UCSF scheduling Millie to start on a new treatment. ref SDS 29
041080 -        KR4P
041082 -         ..
041083 -   23.  On 090123 Glenna called and thanked her for expediting Millie's
041084 -        new treatment to start on 090129 so that cancer does not
041085 -        cascade out of control, ref SDS 30 TR80; request documentation
041086 -        on new treatment in order to be prepared starting on 090129
041087 -        0830, as presented in Glenna's telephone message on 090122,
041088 -        ref SDS 28 AT6N
041090 -         ..
041091 -   24.  On 090123 Glenna advised during her call that there was not
041092 -        enough time to meet with Doctor Rugo on 090121; she received a
041093 -        letter from the doctor to coordinate with Kaiser on getting
041094 -        timely referral to start Millie's next treatment at UCSF on
041095 -        090129. ref SDS 30 118M
041097 -         ..
041098 -   25.  On 090123 Doctor Johnson, Millie's primary care physician at
041099 -        Kaiser, called and confirmed prior advice that Doctor Rugo can
041100 -        prescribe follow on treatment for Millie because her cancer has
041101 -        become resistant to drugs available at Kaiser. ref SDS 33 8K6K
041103 -         ..
041104 -   26.  On 090127 Millie letter to medical team reporting Doctor
041105 -        Johnson called on 090123 to advise of approval for Doctor Rugo
041106 -        to prescribe Millie's follow on treatment at UCSF to start
041107 -        immediately on 090129. ref SDS 35 TY5W
041109 -         ..
041110 -   27.  On 090127 Millie's letter to the medical team submitted patient
041111 -        history to facilitate prescribing new treatment for Millie's
041112 -        6th relapse of IBC. ref SDS 35 TY6S
041114 -         ..
041115 -   28.  On 090127 Millie's letter reported side effects of sunitinib
041116 -        have begun to subside after stopping treatment on 090122 in
041117 -        order to prepare to start new treatment on 090129. ref SDS 35
041118 -        TY8T
041120 -         ..
041121 -   29.  On 090128 Millie letter to primary care physician and the
041122 -        medical team reported IBC worsening, and taking Vicadin for
041123 -        pain. ref SDS 37 2S8X
041125 -         ..
041126 -   30.  On 090129 Doctor Rugo sent a letter to primary care physician
041127 -        at Kaiser requesting referral to UCSF for treatment with
041128 -        hyperthermia and Doxil, reported in Millie's letter to medical
041129 -        team on 090130. ref SDS 44 AY9Q
041131 -         ..
041132 -   31.  On 090130 Millie letter to primary care physician, ref SDS 44
041133 -        GV4M, reports examination at UCSF on 090129 found IBC
041134 -        progressing rapidly, ref SDS 44 4S8O, as Doctor Johnson noted
041135 -        earlier on 090123, ref SDS 33 8K6K;
041137 -         ..
041138 -   32.  On 090130 Millie letter to primary care physician advises UCSF
041139 -        reported communication delay prevented getting referral from
041140 -        Kaiser, which then delayed starting hyperthermia treatment on
041141 -        090129 in time to be effective. ref SDS 44 AY8Q
041143 -         ..
041144 -   33.  On 090130 Millie letter to medical team reports that on 090129
041145 -        coordinating timely referral from Kaiser was delayed because
041146 -        primary care physician was not in the office. ref SDS 44 AY9T
041148 -         ..
041149 -   34.  On 090130 Krshna called Millie to schedule hyperthermia
041150 -        treatment in the Radiation Oncology Department, and said that
041151 -        UCSF has not received referral authorization from Kaiser.
041152 -        ref SDS 42 NM5H
041154 -         ..
041155 -   35.  On 090130 called Arlette, ref SDS 43 RY4G, and she contacted
041156 -        Doctor Johnson off-site in a meeting, and he advised that the
041157 -        doctor would file authorization in the evening on 090130.
041158 -        ref SDS 43 PPYY
041160 -         ..
041161 -   36.  On 090131 Millie received letter from Doctor Johnson, primary
041162 -        care physician, that Kaiser authorization was issued on 090130,
041163 -        ref SDS 45 GV4M, for Millie to get treatment for 6th relapse of
041164 -        IBC with hyperthermia and Doxil, prescribed by Doctor Rugo on
041165 -        090129 (reported in Millie's letter on 090130. ref SDS 44 AY9Q
041167 -         ..
041168 -   37.  On 090201 Millie letter reports to medical team 6th relapse IBC
041169 -        getting worse by the hour requires immediate treatment to
041170 -        prevent cancer from getting out of control.  Pain from IBC
041171 -        makes sleeping difficult. ref SDS 46 KN9T
041173 -         ..
041174 -   38.  On 090201 Millie plans to go to UCSF for treatment tomorrow on
041175 -        090202 when convenient for Doctor Hsu to provide hypethermia
041176 -        treatment. ref SDS 46 KN9W
041178 -         ..
041179 -   39.  On 090201 Millie reports lymphedema recurrence caused by
041180 -        sling-immobilizer to treat dislocated shoulder on 090122;
041181 -        advises Cellulitis did not recur, as previously. ref SDS 46
041182 -        KN4S
041184 -         ..
041185 -   40.  On 090201 Millie reports good news energy recovering after side
041186 -        effects from stopping treatment on sunitinib clinical study
041187 -        ordered by Doctor Rugo on 090122. ref SDS 46 KN4Y
041189 -         ..
041190 -   41.  On 090201 UCSF letter notifies Millie that Doctor Rugo is
041191 -        communicating with Doctor Hsu using email to expedite Millie's
041192 -        treatment; recommends that Millie not come to UCSF on Monday
041193 -        090202 in order to assist the medical team start hyperthermia
041194 -        treatment in time to be effective. ref SDS 47 GV4M
041196 -         ..
041197 -   42.  On 090201 Millie letter assures medical team that the patient
041198 -        would not "camp out" in Doctor Hsu's office, but would stand-by
041199 -        in the cafeteria so that treatment can begin when convenient
041200 -        for UCSF, and without waiting for patient to travel through
041201 -        mid-day traffic, so that urgent treatment is not delayed beyond
041202 -        a point when treatment can no longer be effective. ref SDS 48
041203 -        GV4M
041205 -         ..
041206 -   43.  On 090201 Millie asks Doctor Rugo about coordinating to provide
041207 -        medical records on file in the doctor's office the past 2 years
041208 -        treating Millie at UCSF, ref SDS 48 5R4S, to use by Doctor Hsu,
041209 -        requested by Krshna in a call the day before on 090130.
041210 -        ref SDS 42 DL4J
041212 -         ..
041213 -   44.  On 090201 emotional trauma esclates from delays getting
041214 -        treatment for aggressive cancer that seems to be cascading out
041215 -        of control because of communication delays. ref SDS 48 5R4V
041217 -         ..
041218 -   45.  On 090202 Michelle at UCSF called in the morning, and said
041219 -        Kaiser has not submitted authorization for Millie's treatment
041220 -        by Doctor Hsu. ref SDS 50 9Y5I  Michelle asked the patient to
041221 -        coordinate with the primary care physician at Kaiser to file
041222 -        Authorization, ref SDS 50 9Y6Y, reported in Millie's letter to
041223 -        the medical team. ref SDS 52 GV4M
041225 -         ..
041226 -   46.  On 090202 Michelle was advised that Doctor Johnson reported in
041227 -        a letter on 090131 that Doctor Rugo at UCSF was notified on
041228 -        090130 that Kaiser issued authorization for Millie's treatment,
041229 -        ref SDS 45 GV4M, and further that Doctor Johnson would be out
041230 -        of town for several days, so he is not available on 090202 for
041231 -        coordinating requested by UCSF on 090202, ref SDS 49 Y35M, to
041232 -        file duplicate authorization, reported in Millie's letter to
041233 -        the medical team on 090202 1028. ref SDS 52 FR6P
041235 -         ..
041236 -   47.  On 090202 0940 numerous calls were made to coordinate.
041237 -        ref SDS 51 9Y5I  Florida in Kaiser Oncology Department, Walnut
041238 -        Creek CA advised that Pam in Kaiser Outside Referrals
041239 -        Department said the doctor did not enter a "code" in the
041240 -        Authorization form for hyperthermia treatment, so Pam is
041241 -        waiting to get the code when the doctor returns from traveling
041242 -        sometime in the next few days, ref SDS 51 1A5J, reported in
041243 -        Millie's letter to the medical team. ref SDS 52 FR7R
041245 -         ..
041246 -   48.  On 090202 1012 called Kaiser Outside Referrals and left a
041247 -        message that we need submission of authorization, so that
041248 -        Millie can get treatment in time to be effective. ref SDS 51
041249 -        W17K  Suggested Outside Referrals send written notice to
041250 -        Michelle Williams Jones at UCSF that authorization is on file
041251 -        at Kaiser, and will be submitted to UCSF, so that my treatment
041252 -        can be initiated concurrently. ref SDS 51 254F, reported in
041253 -        Millie's letter to the medical team. ref SDS 52 FR7U
041255 -         ..
041256 -   49.  On 090202 1047 Pam in Outside Referrals at Kaiser called and
041257 -        disclosed that the department needed to know the type of
041258 -        treatment Millie would get on referral to UCSF?  Advised
041259 -        treatment is "hyperthermia," in the Radiation Oncology
041260 -        department at UCSF.  Pam reported that Kaiser does not have a
041261 -        code for "hypethermia" nor for "Radiation Oncology."  Pam used
041262 -        a code for "Radiology."  Problem solved. ref SDS 53 QQ7N, and
041263 -        reported in Millie's letter to the medical team on 090202 1139.
041264 -        ref SDS 55 M88H
041266 -         ..
041267 -   50.  On 090202 1117 Pam called back and wanted to know if referral
041268 -        to UCSF is for in-patient or out-patient treatment?  Since
041269 -        radiation is often out-patient care, and initial discussions
041270 -        did not indicate Millie would require staying in the hospital,
041271 -        Pam coded the form for out-patient care, reported in the record
041272 -        on 090202 1047]. ref SDS 53 0256, and reported in Millie's
041273 -        letter to the medical team on 090202 1139. ref SDS 55 C94Y
041275 -         ..
041276 -   51.  On 090202 1118 Doctor Rugo notified the medical team that
041277 -        Doctor Hsu cannot see Millie on 090202; advises that Doctor Hsu
041278 -        is aware of Millie's situation. ref SDS 54 V47L
041280 -         ..
041281 -   52.  On 090202 1353 Doctor Hsu's assistant, Krshna reported that the
041282 -        doctor was not aware of urgency to treat Millie, cited in
041283 -        Doctor Rugo's letter on 090202 1118. ref SDS 54 V47L   Krshna
041284 -        proposes scheduling the work on 090219, ref SDS 56 XO7G, and
041285 -        does not feel comfortable asking Doctor Hsu to advance the date
041286 -        for treatment, because his schedule is already booked.
041287 -        ref SDS 56 SP8I, reported in Millie's letter to the medical
041288 -        team on 090202 1437. ref SDS 57 R23P
041290 -         ..
041291 -   53.  On 090202 1357 Krshna offers UCSF Radiation Oncology schedule
041292 -        hyperthermia treatment 3 weeks delay to 090219. ref SDS 56 XO7G
041294 -         ..
041295 -   54.  On 090202 1437 Millie notifies medical team that UCSF received
041296 -        Kaiser authorizations for treating the 6th relapse of IBC,
041297 -        ref SDS 57 JR4J, reported on 090202 1353. ref SDS 56 SP6H
041298 -        Millie thanks Doctor Rugo for expediting authorization with
041299 -        Doctor Johnson at Kaiser, citing Doctor Rugo's letter to Doctor
041300 -        Johnson on 090129, reported on 090130, ref SDS 44 TZ6H, Doctor
041301 -        Rugo's letter to medical team on 090202 1118, indicating Doctor
041302 -        Hsu is aware of Millie's situation. ref SDS 54 V47L
041304 -         ..
041305 -   55.  On 090202 1437 IBC disease has advanced significantly since
041306 -        examination at UCSF on 090129, and pain on chest is rising.
041307 -        Since Doctor Rugo has much more experience with IBC, if this
041308 -        just "looks bad," but delaying treatment to 090219 presents no
041309 -        risk of losing control, then I am fine with waiting until the
041310 -        19th. ref SDS 57 R23S
041312 -         ..
041313 -   56.  On 090202 1437 Millie notifies UCSF that Krshna indicated if
041314 -        Doctor Rugo feels earlier treatment is needed, she can notify
041315 -        Doctor Hsu directly. ref SDS 56 F65G, cited in Millie's letter
041316 -        to medical team on 090202 1437, ref SDS 57 R23V
041318 -         ..
041319 -   57.  On 090202 1437 Millie apologizes for adding to Doctor Rugo's
041320 -        work load.  Waiting to the 19th is a shock compared to what
041321 -        Millie sees on her chest.  Results for CA 15-3 from the lab
041322 -        last week on 090129 have not been published, but expect it will
041323 -        be 200+, since it was 303 at Kaiser on 090116. ref SDS 17 PQTQ
041324 -        Those are scary numbers in Millie's patient history.  Millie
041325 -        avers being a "sissy."  Doctor Rugo and others at UCSF and
041326 -        Kaiser are working hard to help Millie and many other patients,
041327 -        cited in Millie's letter to medical team on 090202 1437.
041328 -        ref SDS 57 R23Y
041330 -         ..
041331 -   58.  On 090202 1550 called VCI and asked about Millie getting
041332 -        hyperthermia treatment immediately, rather than wait to 090219
041333 -        offered by UCSF. ref SDS 58 YU8H
041335 -         ..
041336 -   59.  On 090202 1732 letter notifies medical team that Millie needs
041337 -        urgent treatment quickly in time to be effective. ref SDS 59
041338 -        Y15J
041340 -         ..
041341 -   60.  On 090203 0939 call VCI and schedule call to discuss alternate
041342 -        source for Millie to get hyperthermia treatment in time to be
041343 -        effective recovering from 6th relapse of IBC. ref SDS 60 9Y5I
041345 -         ..
041346 -   61.  On 090203 1009 letter to VCI submits patient history for review
041347 -        to support telephone conference, ref SDS 60 IN94, on arranging
041348 -        for VCI to provide hyperthermia treatment in time for Millie to
041349 -        recover from 6th relapse of IBC. ref SDS 60 EP3S
041351 -         ..
041352 -   62.  On 090203 1024 called UCSF talked to Jennette in Radiation
041353 -        Oncology; she will discuss with Doctor Hsu advancing Millie
041354 -        getting hyperthermia treatment from 090219 to this week.
041355 -        ref SDS 61 XX5I
041357 -         ..
041358 -   63.  On 090203 1206 Doctor Al-Bussam called and reported well
041359 -        ordered record for Millie's patient history enabled expedited
041360 -        review of complex medical problems. ref SDS 62 8488, VCI
041361 -        offered to start work the next day on 090204 giving Millie
041362 -        hyperthermia treatment in time to be effective recoverying from
041363 -        6th relapse IBC. ref SDS 62 OE4F
041364 -
041366 -  ..
041367 - Millie sent a letter to the medical team explaining VCI offer to
041368 - provide hyperthermia treatment tomorrow on 090204, in time to be
041369 - effective, and asks for medical opinion comparing this offer with UCSF
041370 - proposal delaying treatment 3 weeks to 090219...
041371 -
041372 -    1.  Subject: IBC Patient History Requires Immediate Hyperthermia
041373 -        Date: Tue, 03 Feb 2009 14:23:34 -0800
041382 -         ..
041383 -    2.  As you know, UCSF has scheduled my treatment with hyperthermia
041384 -        and Doxil on 090219 1000 [reported on 090202 1353, ref SDS 56
041385 -        XO7G, presented in Millie's letter to the medical team on
041386 -        090202 1437, ref SDS 57 R23P].  I [reported disease advanced
041387 -        significantly since examination on 090129, and asked Doctor
041388 -        Rugo for an opinion on whether delaying treatment 3 weeks would
041389 -        be okay [Millie's letter to medical team on 090202 1437.
041390 -        ref SDS 57 R23S
041392 -         ..
041393 -    3.  Doctor [Rugo] wrote a letter to the medical team with a copy to
041394 -        you and to Radiation Oncology at UCSF that I need urgent
041395 -        treatment, and that this should be done quickly. ref SDS 59
041396 -        Y15J
041398 -         ..
041399 -    4.  This morning during a call to UCSF, Jennette in Radiation
041400 -        Oncology said she would talk to Doctor Hsu about advancing my
041401 -        treatment to today, tomorrow, sometime this week, per Doctor
041402 -        Rugo's letter, and would call back to advise. ref SDS 61 XX5I
041404 -         ..
041405 -    5.  Research on hyperthermia treatment [on 090129 after disclosure
041406 -        at UCSF that this was proposed to treat Millie's 6th relapse of
041407 -        IBC, ref SDS 41 QS5H, led to discussion with Valley Cancer
041408 -        Institute (VCI) in Los Angeles [on 090202 1550. ref SDS 58
041409 -        YU8H]
041411 -         ..
041412 -    6.  In a call a few mintues ago, Doctor Al-Bussam says that VCI can
041413 -        start treatment tomorrow on Wednesday, or Thursday, or Friday.
041414 -        ref SDS 62 OE4F
041415 -
041416 -              [On 090203 1438 Jennette with UCSF Radiation Oncology
041417 -              Department called back and advised that Doctor Hsu will
041418 -              begin hypertermia treatment on 090205 so that Millie can
041419 -              recover from 6th relapse of IBC, rather than risk waiting
041420 -              until 090219, as proposed yesterday. ref SDS 63 XX5I
041422 -               ..
041423 -              [On 090203 1444 Millie notifies medical team problem
041424 -              solved; UCSF changed schedule for Millie's hyperthermia
041425 -              treatment to 090205 from prior proposal to start on
041426 -              090219. ref SDS 64 YQ5T
041428 -         ..
041429 -    7.  VCI hyperthermia is performed over an approximate 2 week period
041430 -        on an out-patient protocol, so I would have to stay there for 2
041431 -        weeks.  I need a PET/CT scan to identify IBC fields that get
041432 -        treatment.  This can be done at Kaiser or at VCI.  Assume the
041433 -        same for UCSF.  So, if we do the work at UCSF, should Kaiser
041434 -        schedule a PET/CT scan as well?
041436 -         ..
041437 -    8.  Doctor Al-Bussam says VCI will combine hyperthermia with low
041438 -        dose radiation to treat IBC, and they can combine Doxil as
041439 -        Doctor Rugo prescribes.  Cost is about $40K.
041441 -         ..
041442 -    9.  If UCSF can juggle the schedule to start treatment in the next
041443 -        few days, I would prefer working with Doctor Hsu locally, based
041444 -        on excellent results working with Doctor Rugo.  There is a lot
041445 -        of benefit to close practice collaboration at UCSF.
041446 -
041447 -              [On 090202 1438 Jennette with UCSF Radiation Oncology
041448 -              Department called back and advised that Doctor Hsu will
041449 -              begin hypertermia treatment on 090205 so that Millie can
041450 -              recover from 6th relapse of IBC, rather than risk waiting
041451 -              until 090219, as proposed yesterday. ref SDS 63 XX5I
041453 -         ..
041454 -   10.  Alternatively, a medical opinion should be issued on risks of
041455 -        waiting to Feb 19th against advantages of doing the work
041456 -        tomorrow at VCI.  Here is some research on the VIC hyperthermia
041457 -        program [listed on 090129. ref SDS 41 QS5H]
041458 -
041459 -            [On 090203 Doctor Rugo would not choose VCI for
041460 -            hyperthermia treatment. ref SDS 66 DY4K
041462 -         ..
041463 -   11.  VCI can be reached at:  310-398-0013
041465 -         ..
041466 -   12.  Ask for Nash; she is familiar with Millie's case.  There is not
041467 -        a long wait, no hassle making contact.
041469 -         ..
041470 -   13.  VCI indicates they have treated patients with hyperthermia on
041471 -        referral from UCSF.
041473 -         ..
041474 -   14.  The question is whether treatment at UCSF can be advanced.  If
041475 -        not, is my condition urgent enough to require another provider,
041476 -        and, if so, is VCI a good choice under the circumstances?  Is
041477 -        there another way to get this work done in time to be
041478 -        effective?
041480 -         ..
041481 -   15.  Good news -- lymphedema swelling on left arm reported on 090201
041482 -        has now subsided.
041484 -         ..
041485 -   16.  Bruising has sprung up along my lower right side above the hip.
041486 -
041487 -            [On 090203 2217 in another record today later at night,
041488 -            Millie complains of rising pain in right shoulder and arm,
041489 -            ref SDS 65 KE5I, and further observes expanding and
041490 -            worsening bruising. ref SDS 65 RN6J
041492 -         ..
041493 -   17.  Vicadin and Tylenol with increased dose from the prescription
041494 -        on 090122 are controlling pain from IBC on my chest [reported
041495 -        in Millie's letter yesterday on 090202 1437, ref SDS 57 R23S,
041496 -        and also the day before on 090201 presenting mild pain on scale
041497 -        1 - 10 only 3. ref SDS 46 KN9T].  Hope that's okay.  My
041498 -        shoulder seems to be recovering fine.  No pain, no more
041499 -        swelling.
041500 -
041501 -            [On 090204 1528 Millie reported calling Kaiser on 090203
041502 -            for pain relief from interrupting sleep caused by worsening
041503 -            IBC and shoulder injury, as reported in the record on
041504 -            090203 2217, ref SDS 65 KE5I; Millie advised on 090204 1528
041505 -            implementing Kaiser instructions, ref SDS 67 135F, to
041506 -            double the dose for pain medication, and if pain persists,
041507 -            the doctor will prescribe low-dose morphine, ref SDS 67
041508 -            D64W, resolving fears of over medicating by taking only 30%
041509 -            of prescribed dose levels, also reported on 090203 2217.
041510 -            ref SDS 65 L74H
041512 -         ..
041513 -   18.  Please advise on scheduling hyperthermia treatment.  Do we need
041514 -        to accelerate the schedule?
041515 -
041522 -
041523 -
041524 -
041525 -
041526 -
041527 -
041528 -
041529 -
041530 -
041531 -
0416 -