THE WELCH COMPANY
440 Davis Court #1602
San Francisco, CA 94111-2496
415 781 5700
rodwelch@pacbell.net


S U M M A R Y


DIARY: January 22, 2009 11:21 PM Thursday; Rod Welch

Glenna called left message on Millie starting new treatment next week.

1...Summary/Objective
2...Progression of Cancer 7th Relapse and 6th Relapse of IBC


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CONTACTS 

SUBJECTS
Default Null Subject Account for Blank Record

0403 -
0403 -    ..
0404 - Summary/Objective
0405 -
040501 - Follow up ref SDS 36 0000. ref SDS 28 0000.
040502 -
040503 -
040504 -
040506 -  ..
0406 -
0407 -
0408 - Progress
0409 -
040901 - Background...
040902 -
040903 -    1.  On 090108 examination at UCSF showed possible progression of
040904 -        IBC in breastbone area, cited in Millie's letter to the medical
040905 -        team the next day on 090109. ref SDS 22 UC4H  Millie reported
040906 -        severe side effects in a letter on 090106, ref SDS 19 YO4S,
040907 -        discussed with the medical team at UCSF on 090108, and cited by
040908 -        reference in Millie's letter to the team on 090109. ref SDS 22
040909 -        UF3Q  UCSF prescribed another cycle sunitinib treatment, with
040910 -        cyclophosphamide paused until blood counts increase to a safe
040911 -        level. ref SDS 22 UF3T
040913 -         ..
040914 -    2.  On 090108 Millie received a letter from Glenna summarizing
040915 -        understandings for the work plan presented during the meeting
040916 -        earlier at UCSF on 090108. ref SDS 21 LX7O
040918 -         ..
040919 -    3.  On 090109, Millie submitted a letter to the medical team
040920 -        presenting findings from the examination and transmitting
040921 -        Glenna's work plan summary. ref SDS 22 UC4H
040923 -         ..
040924 -    4.  On 090116 Glenna called about Millie's response to sunitinib
040925 -        treatments. during 3rd cycle of sunitinib. ref SDS 28 JY6L
040926 -        Reviewed record on 090115 reporting IBC rash looks improved to
040927 -        stable, and nodules in the breastbone area seem stable to
040928 -        worse, ref SDS 26 124N, relative to detailed review on 090110,
040929 -        ref SDS 23 124N, and after 7 days of treatment with only
040930 -        sunitinib, and 21 total treatments with sunitinib since the
040931 -        pause on 081218 and resuming on 081226, ref SDS 26 6C4J,
040933 -         ..
040934 -    5.  Millie talked on 090116 morning about reducing the dose of
040935 -        sunitinib in order to reduce side effects. ref SDS 28 JY7J  She
040936 -        seems at this point still committed to trying the current
040937 -        higher dose in order to optimize recovery, planned in the
040938 -        meeting with the medical team on 090108, noted in Millie's
040939 -        letter on 090109. ref SDS 22 UF3T
040941 -         ..
040942 -    6.  Asked Glenna about remedy to relieve side effects, mainly of
040943 -        sore toes that prevent exercise that maintains immune system
040944 -        for recoverying from cancer. ref SDS 28 PPUQ
040946 -         ..
040947 -    7.  On 090116 Millie received Glenna's letter planning a meeting
040948 -        with Doctor Rugo to discuss Millie's case, ref SDS 30 YN9H, and
040949 -        which attached a letter Glenna sent to the doctor describing
040950 -        IBC in the breastbone area has worsened. ref SDS 30 FW3J
040952 -         ..
040953 -    8.  On 090116 Millie's letter to Glenna clarifies breastone area
040954 -        looks stable to worse; everything else looks improved to
040955 -        stable. ref SDS 31 IS6G  Millie further reports rising side
040956 -        effects of treatment, and requests remedy. ref SDS 31 IT4V
040958 -         ..
040959 -    9.  On 090118 Millie talks about wanting to end treatment with
040960 -        sunitinib that seems now less effective and has severe side
040961 -        effects after adding cycloposphamide. ref SDS 32 UC41
040963 -         ..
040964 -   10.  On 090121 Glenna called to discuss patient history showing
040965 -        progression of cancer; Millie's 6th relapse of IBC. ref SDS 36
040966 -        AJ3J  Side effects continue to rise. ref SDS 36 TW53  Glenna
040967 -        asked about Doctor Rugo's plans for follow on treatments.
040968 -        ref SDS 36 Y67L  Glenna wrote a letter to the doctor scheduling
040969 -        a meeting to discuss changing treatment for Millie, ref SDS 36
040970 -        N976, cited previously in Glenna's letter on 090116.
040971 -        ref SDS 30 YN9H
040973 -  ..
040974 - When Millie returned from the hospital late this evening on 090122 and
040975 - after treatment in the Emergency Department for a dislocated shoulder,
040976 - ref SDS 38 0001, there was a telephone message on the answering
040977 - machine from Glenna, ref SDS 38 ZH9O, responding to the telephone
040978 - message calling Glenna earlier today while at the hospital.
040979 - ref SDS 38 W466
040981 -  ..
040982 - Glenna's message reported that she met with Doctor Rugo to develop a
040983 - new treatment plan for Millie, discussed previously in Glenna's call
040984 - yesterday on 090121, ref SDS 36 N976, implementing plans in Glenna's
040985 - letter to Millie on 090116, ref SDS 30 YN9H, and presenting to Doctor
040986 - Rugo the list of treatments which the doctor requested from the
040987 - patient, ref SDS 36 EV53, showing what has been considered for
040988 - Millie's patient profile. ref SDS 36 Y67L
040990 -  ..
040991 - The message said Doctor Rugo has determined Millie has relapsed for
040992 - the 6th time (see below, ref SDS 0 J34U) with progression of IBC,
040993 - reported in patient history on 090120, ref SDS 34 124N, and discussed
040994 - with Glenna on 090121, ref SDS 36 N95K, citing the cancer marker CA
040995 - 15-3 303 rising 100 points in a few weeks, showin in Kaiser's lab last
040996 - on 090116. ref SDS 29 PQTQ  Glenna said the doctor is concerned about
040997 - Millie suffering rising side effects of treatment with sunitinib,
040998 - reported on 090120. ref SDS 34 UC41  Doctor Rugo will meet with Millie
040999 - at the regular time next Thursday 090129 0830 to prescribe Millie's
041000 - next treatment for the 6th relapse of IBC.
041002 -  ..
041003 - The meeting on 090129 will include another doctor to consult with
041004 - Doctor Rugo on Millie's treatment.  Glenna advised that Doctor Rugo
041005 - ordered treatment with sunitinib to end today in order to remove
041006 - toxicity from the body in time for the new treatment to start on
041007 - 090129, after the meeting at 0830, following the usual practice the
041008 - past 2 years at UCSF getting of treatment after examinations.
041010 -  ..
041011 - This aligns with Doctor Johnson's planning on 081219 for Millie to
041012 - start treatment of the 6th relapse in time to be effective before
041013 - cancer that has mutated into a more aggressive disease cascades out of
041014 - control. ref SDS 15 NS8H
041016 -  ..
041017 - Progression of Cancer 7th Relapse and 6th Relapse of IBC
041018 -
041019 - Follow up ref SDS 10 J34U, ref SDS 9 0T8H.
041020 -
041021 -        1.  Lymph node biopsy positive start
041022 -            bevacizumab Taxotere.............. 040318, ref SDS 1 8R6M
041024 -             ..
041025 -        2.  Cancer marker IBC increase end
041026 -            bevacizumab Taxotere due to
041027 -            pulmonary embolism................ 041210, ref SDS 2 025H
041029 -             ..
041030 -        3.  Cancer marker IBC recurs 9 months
041031 -            months after mastectomy........... 060711, ref SDS 3 025H
041033 -             ..
041034 -        4.  Cancer marker IBC worsens end
041035 -            capeticabine Taxotere............. 061201, ref SDS 5 RU6J
041037 -             ..
041038 -        5.  IBC progression with increased
041039 -            lymph nodes in axilla add
041040 -            Carboplatin to cetuximab.......... 080306, ref SDS 9 NW3N
041042 -             ..
041043 -        6.  IBC worsesn CT test shows swelled
041044 -            LN left supraclavicular; treatment
041045 -            cetuximab and Carboplatin end;
041046 -            begin work plan for sunitinib
041047 -            metronomic protocol............... 081016, ref SDS 10 J34U
041049 -             ..
041050 -        7.  IBC symptoms rise aligns with
041051 -            accelerating cancer marker CA 15-3
041052 -            303 Doctor Rugo diagnoses relapse
041053 -            ends treatment on sunitinb
041054 -            protocol.......................... 090122, ref SDS 0 J34U
041055 -
041057 -         ..
041058 -        [On 090123 Millie's letter to medical team reports progress at
041059 -        UCSF scheduling Millie to start on a new treatment. ref SDS 40
041060 -        KR4P
041062 -         ..
041063 -        [On 090123 Glenna called and advised that she has not met with
041064 -        Doctor Rugo due to limited time, and that UCSF has not yet
041065 -        specified a follow on treatment for Millie. ref SDS 41 TR7L
041067 -         ..
041068 -        [On 090123 Doctor Johnson, Millie's primary care physician at
041069 -        Kaiser, called and advised that Doctor Rugo can prescribe
041070 -        follow on treatment for Millie because her cancer has become
041071 -        resistant to drugs available at Kaiser. ref SDS 42 8K6K
041073 -         ..
041074 -        [On 090126 Millie letter to Doctor Stritter reports UCSF
041075 -        ended treatment on sunitinib due to progression of disease
041076 -        and requests immediate input on follow on treatments for
041077 -        Millie's 6th relapse of IBC. ref SDS 43 Q59G
041079 -         ..
041080 -        [On 090127 Millie's letter notified medical team that
041081 -        primary care physician approves UCSF prescribing treatment
041082 -        for Millie's 6th relapse from IBC, because recent rise of
041083 -        cancer marker CA 15-3 303 for the labs at Kaiser on 090116
041084 -        indicated Millie's cancer has mutated to cells that now
041085 -        resist treatments available at Kaiser. ref SDS 44 TY5W
041087 -         ..
041088 -        [On 090127 Millie's letter to medical team reported side
041089 -        effects of sunitinib treatment begin to subside 5 days after
041090 -        UCSF ended treatment with the sunitinib protocol. ref SDS 44
041091 -        TY8T
041093 -         ..
041094 -        [On 090212 0017 Millie's letter to medical team reports
041095 -        rising fatigue, ref SDS 45 1N3U, even after ending
041096 -        chemotherapy on 090122, ref SDS 39 AT6N, and hoping does
041097 -        not signal cancer cascading out of control with CA 15-3 303
041098 -        at Kaiser on 090116, ref SDS 29 PQTQ, cited by primary care
041099 -        physician at Kaiser on 090123. ref SDS 42 RK6O
041101 -         ..
041102 -        [On 090331 2047 8th relapse of cancer, and 7th relapse of IBC
041103 -        occurs on lower left arm, below area treated with radiation and
041104 -        hyperthermia. ref SDS 46 Q69V
041105 -
041106 -
041107 -
041108 -
041109 -
041110 -
0412 -