THE WELCH COMPANY
440 Davis Court #1602
San Francisco, CA 94111-2496
415 781 5700
rodwelch@pacbell.net
S U M M A R Y
DIARY: January 15, 2009 07:00 AM Thursday;
Rod Welch
Millie sunitinib 56 treatments IBC 5th relapse cycle 3 and 7th treatme
1...Summary/Objective
2...Sunitinib Metronomic Treatment Loading Dose Clinical Study UCSF
3...Sunitinib Cyclophosmaide Methotrexate Patient History
4...Side Effects Sunitinib Study with Cyclophosphamide Methotrexate
5...Exercise Hiking Maintain Fitness Strengthen Immune System
6...Case Study on Pateint History Exercising
..............
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CONTACTS
SUBJECTS
Default Null Subject Account for Blank Record
0403 -
0403 - ..
0404 - Summary/Objective
0405 -
040501 - Follow up ref SDS J5 0000. ref SDS J4 0000.
040502 -
040503 -
040504 -
040505 -
040506 -
040508 - ..
0406 -
0407 -
0408 - Progress
0409 -
040901 - Sunitinib Metronomic Treatment Loading Dose Clinical Study UCSF
040902 -
040903 - Follow up ref SDS J5 505G, ref SDS J4 505G.
040904 -
040905 - Background pausing treatment on 081219 for a week enabled Millie's
040906 - blood counts to recover, and resumed on 081226 with sunitinib and
040907 - cyclophosphamide. ref SDS G3 505G On 081230 case study dilemma cancer
040908 - treatmnets cause low blood counts, which prevents getting treatment;
040909 - not getting treatment incerases cancer; UCSF paused treatment for a
040910 - week and prescribed Neupogen to increase blood counts. ref SDS G8 I87N
040911 - On 090108 treatment with sunitinib was continued at full strength, and
040912 - cyclophosphamide was discontinued until blood counts rise above NEUTS
040913 - 1.00, and then cyclophosphamide will be reduced from 7 to 5 days a
040914 - week. ref SDS I2 9V4I
040916 - ..
040917 - IBC rash looks improved to stable, and nodules in the breastbone area
040918 - seem stable to worse relative to detailed review on 090110,
040919 - ref SDS I8 124N, and after 7 days of treatment with only sunitinib,
040920 - and 21 total treatments with sunitinib since the pause on 081218 and
040921 - resuming on 081226, shown below. ref SDS 0 6C4J
040923 - ..
040924 - Today, Millie went to the gym for aerobic exercise; and did not go
040925 - hiking, per below. ref SDS 0 X64F Rising side effects of sunitinib
040926 - cause fagitue, ref SDS 0 LF8M, muscle weakness, ref SDS 0 KL4J, and
040927 - perpherial neuropathy. ref SDS 0 HY8M Millie watched television,
040928 - read, and took a nap. She is feeling worse, similar to symptoms of
040929 - chemotherapy.
040931 - ..
040932 - NEUTS patient history of neutropenia from chemotherapy everyday with
040933 - cyclophosphamide reported in case study on 081205. ref SDS C5 EC5N
040935 - ..
040936 - Neupogen treatments prescribed on 090108 by the medical team at UCSF
040937 - for 090109 and 090110, help maintain blood counts to strengthen the
040938 - immunity system, shown in Millie's letter to the medical team on
040939 - 090109. ref SDS I6 UF3Q On 090110, Millie had the 2nd Neupogen
040940 - treatment at Kaiser. ref SDS I9 P73J
040941 -
040943 - ..
040944 - Sunitinib Cyclophosmaide Methotrexate Patient History
040945 -
040946 - Follow up ref SDS J5 OE6K, ref SDS J4 OE6K.
040947 -
040949 - Cycle 1 begin 081128 after 14 treatmenst sunitinib alone
040950 - Cohort: 3
040952 - ..
040953 - Cycle 2 begin 081218 was paused a week and
040954 - so began on 081226 and without
040955 - methotrexate............................... ref SDS J4 9I6T
040957 - ..
040958 - Cycle 3 began 090109 with only
040959 - sunitinib.................................. ref SDS J4 6C4J
040961 - ..
040962 - Cyclophos Metho
040963 - Sunitinib phamide trexate
040964 - Days Date Time Cycle 37.5 50 5
040965 - =======================================================
040966 - Follow up ref SDS J5 PA8Y, ref SDS J4 PA8Y.
040967 -
040968 - 1. 081114 0700 Load 37.5 0 0 ... ref SDS 94 OE6K
040969 - 2. 081115 0700 Load 75.0 0 0 ... ref SDS 95 OE6K
040970 - 3. 081116 0700 Load 112.5 0 0 ... ref SDS 96 OE6K
040971 - 4. 081117 0700 Load 150.0 0 0 ... ref SDS 97 OE6K
040972 - 5. 081118 0700 Load 187.5 0 0 ... ref SDS A0 OE6K
040973 - 6. 081119 0700 Load 225.0 0 0 ... ref SDS A2 OE6K
040974 - 7. 081120 0700 Load 263.5 0 0 ... ref SDS A3 OE6K
040975 - 8. 081121 0700 Load 301.0 0 0 ... ref SDS A4 OE6K
040976 - 9. 081122 0700 Load 338.5 0 0 ... ref SDS A5 OE6K
040977 - 10. 081123 0700 Load 376.0 0 0 ... ref SDS A6 OE6K
040978 - 11. 081124 0700 Load 413.5 0 0 ... ref SDS A7 OE6K
040979 - 12. 081125 0700 Load 451.0 0 0 ... ref SDS A8 OE6K
040980 - ..
040981 - 13. 081126 0700 Load 488.5 0 0 ... ref SDS A9 OE6K
040982 - ..
040983 - 081126 0820 NEUTS........1.50................... ref SDS B0 PU6K
040985 - ..
040986 - 14. 081127 0700 Load 526.0 0 0 ... ref SDS B1 OE6K
040987 - 15. 081128 0700 1 1 563.5 1 50 1 5 ... ref SDS B4 OE6K
040988 - 16. 081129 0700 1 2 601.0 2 100 2 10 ... ref SDS B7 OE6K
040989 - 17. 081130 0700 1 3 638.5 3 150 2 10 ... ref SDS B8 OE6K
040990 - 18. 081201 0700 1 4 676.0 4 200 2 10 ... ref SDS B9 OE6K
040991 - 19. 081202 0700 1 5 713.5 5 250 2 10 ... ref SDS C1 OE6K
040992 - ..
040993 - 20. 081203 0700 1 6 751.0 6 300 2 10 ... ref SDS C3 OE6K
040994 -
040995 - 081203 0735. NEUTS....... 0.624 ...... .......... ref SDS C2 RN5G
040996 -
040997 - Rate of change per day = 1500 - 624 = 876 / 7
040998 -
040999 - = 120+ per day
041001 - ..
041002 - 21. 081204 0700 1 7 788.5 7 350 2 10 ... ref SDS C4 OE6K
041003 - ..
041004 - 22. 081205 0700 1 8 826.0 8 400 3 15 ... ref SDS C5 OE6K
041005 -
041006 - 081205 1300 Neupogen...... 480 mcg 480......... ref SDS C6 KV84
041008 - ..
041009 - 23. 081206 0700 1 9 863.5 9 450 4 20 ... ref SDS C9 OE6K
041010 -
041011 - 081206 0930 Neupogen...... 480 mcg 960......... ref SDS D0 BI4J
041013 - ..
041014 - 24. 081207 0700 1 10 901.0 10 500 4 20 ... ref SDS D1 OE6K
041015 - 25. 081208 0700 1 11 938.5 11 550 4 20 ... ref SDS D2 OE6K
041016 - 26. 081209 0700 1 12 976.0 12 600 4 20 ... ref SDS D3 OE6K
041017 - ..
041018 - 27. 081210 0700 1 13 1013.5 13 650 4 20 ... ref SDS D5 OE6K
041019 -
041020 - 081210 1301. NEUTS....... 1.085 ................. ref SDS D6 QY6H
041022 - ..
041023 - 28. 081211 0700 1 14 1050.0 14 700 4 20 ... ref SDS D9 OE6K
041024 - ..
041025 - 29. 081212 0700 1 15 1087.5 15 750 5 25 ... ref SDS E1 OE6K
041026 -
041027 - 081212 1115. NEUTS....... 1.054 ................. ref SDS E2 QY6H
041029 - ..
041030 - 30. 081213 0700 1 16 1125.0 16 800 6 30 ... ref SDS E4 OE6K
041031 - 31. 081214 0700 1 17 1162.5 17 850 6 30 ... ref SDS E5 OE6K
041032 - 32. 081215 0700 1 18 1200.0 18 900 6 30 ... ref SDS E6 OE6K
041033 - 33. 081216 0700 1 19 1237.5 19 950 6 30 ... ref SDS E7 OE6K
041034 - ..
041035 - 34. 081217 0700 1 20 1275.0 20 1000 6 30 ... ref SDS E8 OE6K
041036 - 35. 081218 0700 1 21 1312.5 21 1050 canceled.. ref SDS F0 OE6K
041037 -
041038 - 081218 0830. NEUTS....... 0.740 ................. ref SDS F1 QY6H
041040 - ..
041041 - 081219 0700 2 1 paused until 081226........... ref SDS F3 OE6K
041043 - ..
041044 - 081219 1130 Neupogen...... 480 mcg 1440 ........ ref SDS F4 UZ7K
041045 - 081220 0900 Neupogen...... 480 mcg 1920 ........ ref SDS F6 UZ7K
041047 - ..
041048 - 36. 081226 0700 2 1 1350.0 22 1100.............. ref SDS G3 OE6K
041049 - 37. 081227 0700 2 2 1387.5 23 1150.............. ref SDS G5 OE6K
041050 - 38. 081228 0700 2 3 1425.0 24 1200.............. ref SDS G6 OE6K
041051 - 39. 081229 0700 2 4 1462.5 25 1250.............. ref SDS G7 OE6K
041052 - 40. 081230 0700 2 5 1500.0 26 1300.............. ref SDS G9 OE6K
041053 - 41. 081231 0700 2 6 1537.5 27 1350.............. ref SDS H1 OE6K
041054 - 42. 090101 0700 2 7 1575.0 28 1400.............. ref SDS H2 OE6K
041055 - 43. 090102 0700 2 8 1612.5 29 1450.............. ref SDS H3 OE6K
041056 - 44. 090103 0700 2 9 1650.0 30 1500.............. ref SDS H4 OE6K
041057 - 45. 090104 0700 2 10 1687.5 31 1550.............. ref SDS H5 OE6K
041058 - 46. 090105 0700 2 11 1725.0 32 1600.............. ref SDS H6 OE6K
041059 - 47. 090106 0700 2 12 1762.5 33 1650.............. ref SDS H8 OE6K
041060 - 48. 090107 0700 2 13 1800.0 34 1700.............. ref SDS I1 OE6K
041061 - ..
041062 - 49. 090108 0700 2 14 1837.5 35 1750.............. ref SDS I2 OE6K
041063 - ..
041064 - 50. 090109 0700 3 1 1875.0..paused................ ref SDS I7 OE6K
041065 - ..
041066 - 51. 090110 0700 3 2 1910.5..paused................ ref SDS I8 OE6K
041067 - 52. 090111 0700 3 3 1948.0..paused................ ref SDS J0 OE6K
041068 - 53. 090112 0700 3 4 1985.5..paused................ ref SDS J1 OE6K
041069 - 54. 090113 0700 3 5 2023.0..paused................ ref SDS J4 OE6K
041070 - 55. 090114 0700 3 6 2060.5..paused................ ref SDS J5 OE6K
041071 - 56. 090115 0700 3 7 2098.0..paused................ ref SDS 0 OE6K
041072 -
041073 -
041074 -
041075 -
041076 -
0411 -
SUBJECTS
Default Null Subject Account for Blank Record
0503 -
050401 - ..
050402 - Side Effects Sunitinib Study with Cyclophosphamide Methotrexate
050403 -
050404 - Follow up ref SDS J5 LF8M, ref SDS J4 LF8M.
050405 -
050406 - Fatigue is a likely side effect of sunitinib with cyclophosphamide,
050407 - listed in the Consent document reviewed on 081017. ref SDS 76 4G7G
050409 - ..
050410 - Blood counts NEUTS 0.87 reported for labs on 090108 at UCSF,
050411 - ref SDS I3 QY6H, show another significant decline from NEUTS 1.710
050412 - reported on 081226, ref SDS G4 B35J, as a result of getting 21 daily
050413 - cancer treatments starting on 081226, shown by patient history above.
050414 - ref SDS 0 9I6T Low blood counts are side affects for some patients of
050415 - sunitinib, listed on 081017, ref SDS 76 ZP5L, that contribute to
050416 - fatigue, also listed as the primary side effect of sunitinib.
050417 - ref SDS 76 4G7G Chemotherapy also causes low blood counts, which
050418 - compounds the problem of fatigue that prevents exercise, causing
050419 - fitness to decline, shown by case study below. ref SDS 0 X64F Lack
050420 - of exercise weakens the immune system, enabling cancer and other
050421 - disease to rise. Since the doctor paused cyclophosphamide
050422 - chemotherapy for a week on 090108, ref SDS I2 9V4I, this may reduce
050423 - the problem of lower blood counts and so help relieve fatigue.
050424 - Additionally, Neupogen treatments on 090109 and 090110 ref SDS J0
050425 - RG7J, prescribed by medical team at UCSF on 090108, ref SDS I2 9V4I,
050426 - further enable blood counts to rise so that treatment with sunitinib
050427 - can continue at full strength, explained in Millie's letter to the
050428 - medical team on 090109. ref SDS I6 UF3T A blood test will be
050429 - performed at Kaiser next Friday on 090116; if NEUTS > 1.00
050430 - cyclophsphamide will be continued at reduced dose of 5 days per week,
050431 - instead 7. ref SDS I6 UF3W This aligns with letter from UCSF on
050432 - 090108 summarizing instructions from medical team. ref SDS I5 UX5S
050434 - ..
050435 - Millie went to the gym for aerobics today; she did not go hiking at
050436 - Lafayette reservoir. She seemed more energetic this morning. She
050437 - reported pain in her toes was tolerable during exercise, and seemed to
050438 - increase an hour or so later. On 090111, and the day before on 090110
050439 - Millie had severe pain in her feet (again mostly toes), discussed
050440 - below, ref SDS 0 HY8M, and muscle weakness in the legs, while hiking
050441 - at Lafayette on 090111, ref SDS J0 3E4K, which are listed as a
050442 - separate side effect of sunitinib on 081017. ref SDS 76 4G7G Millie's
050443 - legs tire quickly, reported below, ref SDS 0 3E4K, cited previously on
050444 - 090102. ref SDS H3 6E7G Increased exercise today despite increased
050445 - fatigue from 21 cancer treatments beginning on 081226, shown above,
050446 - ref SDS 0 9I6T, may reflect in part blood counts rising after getting
050447 - 2 Neupogen treatments, and pausing treatment with cyclophosphamide on
050448 - 090109, per above. ref SDS 0 6M7G
050449 -
050450 - [On 090116 detailed explanation of side effects submitted to
050451 - the medical team. ref SDS J6 IT4Y
050453 - ..
050454 - Background on Neupogen treatments and UCSF comments are reported on
050455 - 081207. ref SDS D1 673J
050457 - ..
050458 - NEUTS blood tests show patient history of treatments with Nuepogen to
050459 - recover from neutropenia caused by getting chemotherapy everyday with
050460 - cyclophosphamide reported in case study on 081205. ref SDS C5 EC5N
050462 - ..
050463 - Schedule for Neupogen treatments is listed in the record on 090110.
050464 - ref SDS I9 HS5M
050466 - ..
050467 - Neupogen treatments prescribed on 090108 by the medical team at UCSF
050468 - for 090109 and 090110, help maintain blood counts to strengthen the
050469 - immune system, shown in Millie's letter to the medical team on 090109.
050470 - ref SDS I6 UF3Q On 090110, Millie had the 2nd Neupogen treatment at
050471 - Kaiser. ref SDS I9 P73J
050473 - ..
050474 - Feet and mostly toes very sensitive from peripheral neuropathy caused
050475 - by side effects of sunitinib, reported on 090112, ref SDS J1 HY8M, and
050476 - citing possible dilemma about treatment with cyclophosphamide.
050477 - ref SDS J1 OG9G Millie went to the gym and did aerobic exercise,
050478 - shown below. ref SDS 0 X64F She reported that exercise was tolerated
050479 - well; about an hour later pain in her feet and toes increased from
050480 - walking through the store shopping for groceries.
050482 - ..
050483 - Tearing eyes reported during examination on 090108; Tara, ref SDS I4
050484 - XB3M, prescribed over-the-counter eye drops.
050486 - ..
050487 - Joint pain, discomfort, and total ill feeling, commonly associated
050488 - with chemotherapy, reported on 081218, ref SDS F0 E38H, and discussed
050489 - with the medical team at UCSF also on 081218, ref SDS F2 QW7H, mostly
050490 - disipated, as a result of the doctor stopping all treatment for 1
050491 - week, ref SDS F2 QW48, as shown in patient history above, ref SDS 0
050492 - 053F, but has begun to rise again.
050494 - ..
050495 - Interstitional lung disease discussed in the record on 081218,
050496 - ref SDS F0 KM5F, shows no evident symptoms.
050498 - ..
050499 - Vitals were taken today at home after minimal activity sitting up in
050500 - bed reading, and walking about the house.
050501 -
050502 - BP 152 74 pulse 48
050504 - ..
050505 - Millie reports continued relief from heartburn with daily treatments
050506 - using Prilosce started on 081208. ref SDS D2 7J6K
050508 - ..
050509 - Coughing from dry throat in the late evening while in bed woke Millie
050510 - from sleep. This continued for about 10 minutes. She had a scoop of
050511 - ice cream about 9pm. The ice cream relieved her throat and stopped
050512 - the coughing.
050514 - ..
050515 - Sore throat problem, reported initially on 081218, as having begun
050516 - days earlier, ref SDS F0 2B8M, may be related to cough from dry throat
050517 - today, after reporting relief so that swallowing became more normal on
050518 - 081222. ref SDS F8 TT4O
050520 - ..
050521 - Millie reports improved taste from some foods today (e.g., soup),
050522 - cited in study consent documents, reviewed on 081017. ref SDS 76 6T5H
050524 - ..
050525 - Date
050526 - Description Adverse Event Start Stop Medication
050527 - ---------------------------------------------------------
050528 - Follow up ref SDS J5 MV5H, ref SDS J4 MV5H.
050529 -
050530 - Diarrhea 081114 081114 Imodium........ ref SDS 94 LF8M
050531 - Low pulse 081120 081120 None........... ref SDS A3 LF8M
050532 - Low pulse 081121 081121 None........... ref SDS A4 7G8M
050533 - BP 144 84 Pulse 48 081121 081121 Hiking......... ref SDS A4 LF8M
050534 - Joint pain minor 081121 081121 Hiking......... ref SDS A4 LF8M
050535 - Fatigue minor 081121 081121 Hiking......... ref SDS A4 LF8M
050536 - Low pulse 081122 081122 None........... ref SDS A5 7G8M
050537 - Fatigue minor 081122 081122 Hiking......... ref SDS A5 LF8M
050538 - Low pulse 081123 081122 None........... ref SDS A6 7G8M
050539 - BP 121 74 Pulse 53 081123 081123 Hiking......... ref SDS A6 LF8M
050540 - Fatigue minor 081123 081122 Hiking......... ref SDS A6 LF8M
050541 - Joint pain minor 081124 081124 Hiking......... ref SDS A7 LF8M
050542 - Fatigue minor 081124 081124 Hiking......... ref SDS A7 LF8M
050543 - Heartburn 081124 081124 None........... ref SDS A7 HS9K
050544 - BP 144 78 Pulse 52 081125 081125 Hiking......... ref SDS A8 LF8M
050545 - Joint pain minor 081125 081125 Hiking......... ref SDS A8 LF8M
050546 - Fatigue minor 081125 081125 Hiking......... ref SDS A8 LF8M
050547 - Heartburn 081125 081125 None........... ref SDS A8 HS9K
050548 - Heartburn 081126 081126 None........... ref SDS A9 HS9K
050549 - Heartburn 081127 081127 None........... ref SDS B3 HS9K
050550 - BP 135 73 Pulse 48 081128 081128 Hiking......... ref SDS B4 5X6K
050551 - Upset stomach 081128 081128 Hiking......... ref SDS B4 T76O
050552 - BP 140 75 Pulse 50 081129 081129 Hiking......... ref SDS B7 5X6K
050553 - Heartburn 081129 081129 None........... ref SDS B7 HS9K
050554 - ..
050555 - Fatigue 081129 081129 Rest........... ref SDS B7 LF8M
050556 - Fatigue 081130 081130 Rest........... ref SDS B8 LF8M
050557 - BP 136 79 Pulse 46 081201 081201 Hiking......... ref SDS B9 5X6K
050558 - Fatigue 081201 081201 Rest........... ref SDS B9 LF8M
050559 - Taste altered 081201 081201 Rest........... ref SDS B9 VP4G
050560 - BP 141 77 Pulse 46 081202 081202 Aerobics gym... ref SDS C1 5X6K
050561 - Fatigue 081202 081202 Rest........... ref SDS C1 LF8M
050562 - Taste altered 081202 081202 Rest........... ref SDS C1 VP4G
050563 - BP 138 77 Pulse 48 081203 081203 Hiking......... ref SDS C3 5X6K
050564 - Fatigue 081203 081203 Rest........... ref SDS C3 LF8M
050565 - Taste altered 081203 081203 Rest........... ref SDS C3 VP4G
050566 - NEUTS (ANC) 0.624 081203 081203 Neupogen.......
050567 - BP 133 72 Pulse 45 081204 081204 Rest........... ref SDS C4 5X6K
050568 - Fatigue 081204 081204 Rest........... ref SDS C4 LF8M
050569 - Taste altered 081204 081204 Rest........... ref SDS C4 VP4G
050570 - BP 138 76 Pulse 49 081205 081205 Rest........... ref SDS C5 5X6K
050571 - Diarrhea 081205 081114 Imodium........ ref SDS C5 Q67F
050572 - Fatigue 081205 081205 Rest........... ref SDS C5 LF8M
050573 - Taste altered 081205 081205 Rest........... ref SDS C5 VP4G
050574 - BP *** ** Pulse ** 081206 081206 Rest........... ref SDS C9 5X6K
050575 - Fatigue 081206 081206 Rest........... ref SDS C9 LF8M
050576 - BP 128 70 Pulse 53 081207 081207 Hiking......... ref SDS D1 5X6K
050577 - Fatigue 081207 081207 Rest........... ref SDS D1 LF8M
050578 - BP 137 68 Pulse 53 081208 081208 Rest........... ref SDS D2 5X6K
050579 - Fatigue 081208 081208 Rest........... ref SDS D2 LF8M
050580 - BP *** ** Pulse ** 081209 081209 Rest........... ref SDS D2 5X6K
050581 - Fatigue 081209 081209 Rest........... ref SDS D2 LF8M
050582 - Heartburn 081209 081209 Prilosec....... ref SDS D3 7J6K
050583 - BP 136 70 Pulse 53 081210 081210 Rest........... ref SDS D5 5X6K
050584 - Fatigue 081210 081210 Rest........... ref SDS D5 LF8M
050585 - Heartburn 081210 081210 Prilosec....... ref SDS D5 7J6K
050586 - BP *** ** Pulse ** 081211 081211 Rest........... ref SDS D9 5X6K
050587 - Fatigue 081211 081211 Exercise gym... ref SDS D9 LF8M
050588 - Heartburn 081211 081211 Prilosec....... ref SDS D9 7J6K
050589 - BP 137 76 Pulse 53 081212 081212 Rest........... ref SDS E1 5X6K
050590 - Fatigue 081212 081212 Exercise gym... ref SDS E1 LF8M
050591 - Heartburn 081212 081212 Prilosec....... ref SDS E1 7J6K
050592 - BP 147 80 Pulse 51 081213 081213 Rest........... ref SDS E4 5X6K
050593 - Fatigue 081213 081213 Exercise gym... ref SDS E4 LF8M
050594 - BP *** ** Pulse ** 081214 081214 Rest........... ref SDS E5 5X6K
050595 - Fatigue 081214 081214 Rest........... ref SDS E5 LF8M
050596 - BP *** ** Pulse ** 081215 081215 Rest........... ref SDS E6 5X6K
050597 - Fatigue 081215 081215 Rest........... ref SDS E6 LF8M
050598 - BP 144 79 Pulse 54 081216 081216 Rest........... ref SDS E7 5X6K
050599 - Fatigue 081216 081216 Exercise gym... ref SDS E7 LF8M
050600 - ..
050601 - Joint pain minor 081216 081216 Rest........... ref SDS E7 E38H
050602 - BP 137 69 Pulse 63 081217 081217 Rest........... ref SDS E8 5X6K
050603 - Fatigue 081217 081217 Rest........... ref SDS E8 LF8M
050604 - Feet toes neuropathy 081216 081217 Rest........... ref SDS E8 HY8M
050605 - Joint pain minor 081217 081217 Rest........... ref SDS E8 E38H
050606 - Nosebleed minor 081217 081217 Rest........... ref SDS E8 ZF5F
050607 - ..
050608 - BP *** ** Pulse ** 081218 081218 Rest........... ref SDS F0 5X6K
050609 - Fatigue 081218 081218 Rest........... ref SDS F0 LF8M
050610 - Joint pain minor 081218 081218 Rest........... ref SDS F0 E38H
050611 - Nosebleed moderate 081218 081218 Rest........... ref SDS F0 ZF5F
050612 - Throat pain eating 081218 081218 Eating less.... ref SDS F0 2B8M
050613 - Feet toes neuropathy 081216 081218 Rest........... ref SDS F0 HY8M
050614 - BP 155 84 Pulse 53 081219 081219 Rest........... ref SDS F3 5X6K
050615 - Fatigue 081121 081219 Rest........... ref SDS F3 LF8M
050616 - Feet toes neuropathy 081216 081219 Rest........... ref SDS F3 HY8M
050617 - Joint pain ill feeling 081121 081219 Rest........... ref SDS F3 E38H
050618 - Throat sore eating 081218 081219 Eating less.... ref SDS F3 TT4O
050619 - BP 123 69 pulse 53 081220 081220 Rest........... ref SDS F5 5X6K
050620 - Fatigue 081121 081220 Rest........... ref SDS F5 LF8M
050621 - Feet toes neuropathy 081216 081220 Rest........... ref SDS F5 HY8M
050622 - Joint pain ill feeling 081121 081220 Rest........... ref SDS F5 E38H
050623 - Throat sore eating 081218 081220 Eating less.... ref SDS F5 TT4O
050624 - BP 117 71 pulse 65 081221 081221 Rest........... ref SDS F7 5X6K
050625 - Fatigue 081121 081221 Rest........... ref SDS F7 LF8M
050626 - Feet toes neuropathy 081216 081221 Rest........... ref SDS F7 HY8M
050627 - Joint pain ill feeling 081121 081221 Rest........... ref SDS F7 E38H
050628 - Throat sore eating 081218 081221 Eating less.... ref SDS F7 TT4O
050629 - BP 117 71 pulse 65 081222 081222 Rest........... ref SDS F8 5X6K
050630 - Fatigue 081121 081222 Rest........... ref SDS F8 LF8M
050631 - Feet toes neuropathy 081216 081222 Rest........... ref SDS F8 HY8M
050632 - Joint pain ill feeling 081121 081222 Rest........... ref SDS F8 E38H
050633 - Throat sore eating 081218 081222 Eating less.... ref SDS F8 TT4O
050634 - BP 143 68 pulse 65 081223 081223 Rest........... ref SDS F8 5X6K
050635 - Fatigue more energy 081121 081223 Exercise gym... ref SDS F9 LF8M
050636 - Feet toes neuropathy better 081219 081223 Exercise gym... ref SDS F9 HY8M
050637 - Joint pain subsides 081121 081223 Exercise gym... ref SDS F9 E38H
050638 - Throat sore improved 081218 081223 Eating normal.. ref SDS F9 TT4O
050639 - BP *** ** pulse ** 081224 081224 Rest........... ref SDS G1 5X6K
050640 - Fatigue more energy 081121 081224 Exercise gym... ref SDS G1 LF8M
050641 - Feet feel better 081219 081224 Exercise gym... ref SDS G1 UO8I
050642 - Joint pain subsides 081121 081224 Exercise gym... ref SDS G1 E38H
050643 - Throat sore improved 081218 081224 Eating normal.. ref SDS G1 TT4O
050644 - BP 124 80 pulse 66 081225 081225 Rest........... ref SDS G2 5X6K
050645 - Fatigue more energy 081121 081225 Activity....... ref SDS G2 LF8M
050646 - Fatigue more energy 081121 081226 Activity....... ref SDS G3 LF8M
050647 - BP *** ** pulse ** 081227 081227 Rest........... ref SDS G5 5X6K
050648 - Fatigue more energy 081121 081227 Hiking......... ref SDS G5 LF8M
050649 - BP *** ** pulse ** 081228 081228 Rest........... ref SDS G6 5X6K
050650 - Fatigue more energy 081121 081228 Rest........... ref SDS G6 LF8M
050651 - BP 112 76 pulse 63 081229 081229 Rest........... ref SDS G7 5X6K
050652 - Fatigue more energy 081121 081229 Rest........... ref SDS G7 LF8M
050653 - BP *** ** pulse ** 081230 081230 Rest........... ref SDS G9 5X6K
050654 - Diarrhea 081230 081230 Imodium........ ref SDS G9 KZ9N
050655 - Fatigue more energy 081121 081230 Rest........... ref SDS G9 LF8M
050656 - BP *** ** pulse ** 081231 081231 Rest........... ref SDS H1 5X6K
050657 - Fatigue more energy 081121 081231 Rest........... ref SDS H1 LF8M
050658 - BP *** ** pulse ** 090101 090101 Rest........... ref SDS H2 5X6K
050659 - Fatigue more energy 081121 090101 Hiking......... ref SDS H2 LF8M
050660 - BP *** ** pulse ** 090102 090102 Rest........... ref SDS H3 5X6K
050661 - Fatigue more energy 081121 090102 Hiking......... ref SDS H3 LF8M
050662 - BP *** ** pulse ** 090103 090103 Rest........... ref SDS H4 5X6K
050663 - Fatigue less energy 081121 090103 Exercise gym... ref SDS H4 LF8M
050664 - BP *** ** pulse ** 090104 090104 Rest........... ref SDS H5 5X6K
050665 - Fatigue less energy 081121 090104 Rest........... ref SDS H5 LF8M
050666 - BP *** ** pulse ** 090105 090105 Rest........... ref SDS H6 5X6K
050667 - Fatigue less energy 081121 090105 Rest........... ref SDS H6 LF8M
050668 - BP *** ** pulse ** 090106 090106 Rest........... ref SDS H8 5X6K
050669 - Fatigue less energy 081121 090106 Exercise gym... ref SDS H8 LF8M
050670 - BP *** ** pulse ** 090107 090107 Rest........... ref SDS H8 5X6K
050671 - Fatigue less energy 081121 090107 Rest........... ref SDS I1 LF8M
050672 - BP *** ** pulse ** 090108 090108 Rest........... ref SDS I2 5X6K
050673 - Fatigue less energy 081121 090108 Rest........... ref SDS I2 LF8M
050674 - Eyes tearing 090108 090108 Eye drops...... ref SDS I2 518H
050675 - BP *** ** pulse ** 090109 090109 Rest........... ref SDS I7 5X6K
050676 - Fatigue less energy 081121 090109 Rest........... ref SDS I7 LF8M
050677 - Eyes tearing 090108 090109 Eye drops...... ref SDS I7 518H
050678 - BP *** ** pulse ** 090110 090110 Rest........... ref SDS I8 5X6K
050679 - Fatigue less energy 081121 090110 Hiking......... ref SDS I8 LF8M
050680 - Eyes tearing 090108 090110 Eye drops...... ref SDS I8 518H
050681 - BP *** ** pulse ** 090111 090111 Rest........... ref SDS J0 5X6K
050682 - Fatigue more energy 081121 090111 Hiking......... ref SDS J0 LF8M
050683 - Eyes tearing 090108 090111 Eye drops...... ref SDS J0 518H
050684 - Feet toes neuropathy 090111 090111 Hiking......... ref SDS J0 HY8M
050685 - BP 144 78 pulse 54 090112 090112 Rest........... ref SDS J1 5X6K
050686 - Fatigue more energy 081121 090112 rest........... ref SDS J1 LF8M
050687 - Eyes tearing 090108 090112 Eye drops...... ref SDS J1 518H
050688 - Feet toes neuropathy 090111 090112 rest........... ref SDS J1 HY8M
050689 - BP 153 74 pulse 49 090113 090113 Rest........... ref SDS J4 5X6K
050690 - Fatigue more energy 081121 090113 Exercise gym... ref SDS J4 LF8M
050691 - Eyes tearing 090108 090113 Eye drops...... ref SDS J4 518H
050692 - Feet toes neuropathy 090111 090113 Exercise gym... ref SDS J4 HY8M
050693 - Diarrhea 090113 090113 Imodium........ ref SDS J4 KZ9N
050694 - BP 147 69 pulse 51 090114 090114 Rest........... ref SDS J5 5X6K
050695 - Fatigue more energy 081121 090114 Rest........... ref SDS J5 LF8M
050696 - Eyes tearing 090108 090114 Eye drops...... ref SDS J5 518H
050697 - Feet toes neuropathy 090111 090114 Rest........... ref SDS J5 HY8M
050698 - BP 152 74 pulse 48 090115 090115 Rest........... ref SDS 0 5X6K
050699 - Fatigue more energy 081121 090115 Exercise gym... ref SDS 0 LF8M
050700 - Eyes tearing 090108 090115 Eye drops...... ref SDS 0 518H
050701 - Feet toes neuropathy 090111 090115 Exercise gym... ref SDS 0 HY8M
050702 - Cough dry throat 090115 090115 Ice cream...... ref SDS 0 R66J
050703 -
050704 -
050705 -
0508 -
SUBJECTS
Default Null Subject Account for Blank Record
0603 -
060401 - ..
060402 - Exercise Hiking Maintain Fitness Strengthen Immune System
060403 -
060404 - Follow up ref SDS J5 3E4K, ref SDS J4 3E4K.
060405 -
060406 - Today, Millie went to the gym for aerobic exercise; she did not hike
060407 - at Lafayette reservoir due to rising...
060408 -
060409 - Fatigue............................... ref SDS 0 LF8M
060410 - Muscle weakness....................... ref SDS 0 KL4J
060411 - Perpherial neuropathy
060412 - pain in feet and mostly toes.......... ref SDS 0 HY8M
060414 - ..
060415 - Increased work outs in the gym help replace loss of fitness from less
060416 - exercise hiking at Lafayette reservoir.
060418 - ..
060419 - Aerobic exercise for an hour at the gym was tolerated well. Millie
060420 - reported she did the entire routine without severe fatigue in her
060421 - legs, nor pain in her toes from peripheral neuropathy caused by
060422 - sunitinib. On the way home, she stopped for groceries at Safeway.
060423 - Walking around the store was difficult on Millie's legs and toes,
060424 - reported previously on 090102, ref SDS H3 6E7G, due to rising side
060425 - effects of fatigue from 21 cancer treatments beginning on 081226.
060426 - ref SDS 0 9I6T Neupogen treatments on 090109 and on 090110, and
060427 - pausing cyclophosphamide may enable blood counts and energy to rise,
060428 - per above. ref SDS 0 LF8M
060430 - ..
060431 - NEUTS blood tests show patient history treatments with Nuepogen for
060432 - neutropenia from chemotherapy everyday with cyclophosphamide reported
060433 - in case study on 081205. ref SDS C5 EC5N
060435 - ..
060436 - On 081110, Millie complained about difficulty lifting herself from a
060437 - full squatting position. ref SDS 90 HX67 For several weeks, she was
060438 - exercising to strengthen legs, and arms, shown by going to the gym on
060439 - 081211. ref SDS D9 3E4K Rising fatigue now prevents continuing
060440 - exercise.
060441 -
060443 - ..
060444 - Case Study on Pateint History Exercising
060445 -
060446 - Follow up ref SDS J5 X64F, ref SDS J4 X64F.
060447 -
060448 - +- scm = Sunitinib Cyclophosphmaide Methotrexate
060449 - +- sc = Sunitinib Cyclophosphmaide
060450 - Time Pulse |
060451 - Location Miles Minutes Avg Max Chem Neupo Date
060452 - ----------------------------------------------------------------
060453 - Concord home (gym) s 090115, ref SDS 0 3E4K
060454 - Concord home s 090114, ref SDS J5 3E4K
060455 - Concord home (gym) s 090113, ref SDS J4 3E4K
060456 - Concord home s 090112, ref SDS J1 3E4K
060457 - Lafayette 4.75 90.4 95 111 s 090111, ref SDS J0 3E4K
060458 - Lafayette 2.75 58.9 85 105 s 090110, ref SDS I8 3E4K
060459 - Concord home s 090109, ref SDS I7 3E4K
060460 - Concord home sc 090108, ref SDS I2 3E4K
060461 - Concord home sc 090107, ref SDS I1 3E4K
060462 - Concord home (gym) sc 090106, ref SDS H8 3E4K
060463 - Concord home sc 090105, ref SDS H6 3E4K
060464 - Concord home sc 090104, ref SDS H5 3E4K
060465 - Concord home (gym) sc 090103, ref SDS H4 3E4K
060466 - Clayton Safeway 3.00 58.7 83 94 sc 090102, ref SDS H3 3E4K
060467 - Lafayette 2.75 58.4 87 103 sc 090101, ref SDS H2 3E4K
060468 - Concord home sc 081231, ref SDS H1 3E4K
060469 - Concord home sc 081230, ref SDS G9 3E4K
060470 - Concord home sc 081229, ref SDS G7 3E4K
060471 - Concord home sc 081228, ref SDS G6 3E4K
060472 - Lafayette 2.75 56.2 90 112 sc 081227, ref SDS G5 3E4K
060473 - Concord home sc 081226, ref SDS G3 3E4K
060474 - Concord travel 081225, ref SDS G2 3E4K
060475 - Concord home 081224, ref SDS G1 3E4K
060476 - Concord home (gym) 081223, ref SDS F9 3E4K
060477 - Concord home 081222, ref SDS F8 3E4K
060478 - Concord home 081221, ref SDS F7 3E4K
060479 - Concord home 081220, ref SDS F5 3E4K
060480 - Concord home 081219, ref SDS F3 3E4K
060481 - Concord home sc 081218, ref SDS F0 3E4K
060482 - Concord home sc 081217, ref SDS E8 3E4K
060483 - Concord home (gym) sc 081216, ref SDS E7 3E4K
060484 - Concord home sc 081215, ref SDS E6 3E4K
060485 - Concord home sc 081214, ref SDS E5 3E4K
060486 - Concord home (gym) scm 081213, ref SDS E4 3E4K
060487 - Concord home scm 081212, ref SDS E1 3E4K
060488 - Concord home (gym) sc 081211, ref SDS D9 3E4K
060489 - Concord home sc 081210, ref SDS D5 3E4K
060490 - Concord home sc 081209, ref SDS D3 3E4K
060491 - Concord home sc 081208, ref SDS D2 3E4K
060492 - Lafayette 4.75 78.6 95 110 sc 081207, ref SDS D1 3E4K
060493 - Concord home scm 081206, ref SDS C9 3E4K
060494 - Concord home scm 081205, ref SDS C5 3E4K
060495 - Concord home sc 081204, ref SDS C4 3E4K
060496 - Lafayette 2.75 62.7 90 117 sc 081203, ref SDS C3 3E4K
060497 - Concord home (gym) sc 081202, ref SDS C1 3E4K
060498 - Lafayette 5.50 102.3 95 122 sc 081201, ref SDS B9 3E4K
060499 - Concord home sc 081130, ref SDS B8 3E4K
060500 - Lafayette 2.75 56.7 90 115 scm 081129, ref SDS B7 3E4K
060501 - Lafayette 2.75 46.5 100 128 scm 081128, ref SDS B4 3E4K
060502 - Lafayette 5.50 93.3 100 122 s 081127, ref SDS B3 3E4K
060503 - Concord home s 081126, ref SDS A9 3E4K
060504 - Lafayette 4.00 73.7 105 127 s 081125, ref SDS A8 3E4K
060505 - Lafayette 5.50 91.4 100 129 s 081124, ref SDS A7 3E4K
060506 - Concord home s 081123, ref SDS A6 3E4K
060507 - Lafayette 5.50 92.8 95 122 s 081122, ref SDS A5 3E4K
060508 - Lafayette 5.50 94.4 85 112 s 081121, ref SDS A4 3E4K
060509 - Lafayette 5.50 94.7 90 122 s 081120, ref SDS A3 3E4K
060510 - San Francisco 1.00 60.0 65 75 s 081119, ref SDS A2 3E4K
060511 - Lafayette 2.75 49.2 97 130 s 081118, ref SDS A1 3E4K
060512 - Lafayette 5.50 93.6 115 138 s 081117, ref SDS 98 3E4K
060513 - Concord home s 081116, ref SDS 96 Y68J
060514 - Concord home s 081115, ref SDS 95 EK7I
060515 - Concord home s 081114, ref SDS 94 XW6H
060516 - Lafayette 5.50 94.2 115 138 081110, ref SDS 90 3E4K
060517 - Lafayette 2.75 48.4 105 128 081109, ref SDS 89 3E4K
060518 - Kaiser x 081108, ref SDS 88 UZ7K
060519 - Kaiser x 081107, ref SDS 87 UZ7K
060520 - Lafayette 5.50 90.2 120 143 081025, ref SDS 83 3E4K
060521 - Kaiser x 081025, ref SDS 83 UZ7K
060522 - Kaiser x 081024, ref SDS 82 UZ7K
060523 - UCSF c 081023, ref SDS 81 V94O
060524 - Lafayette 5.50 90.6 115 141 081021, ref SDS 80 3E4K
060525 - Lafayette 5.50 90.4 110 128 081020, ref SDS 79 3E4K
060526 - Kaiser x 081018, ref SDS 78 UZ7K
060527 - Kaiser x 081017, ref SDS 77 UZ7K
060528 - UCSF e 081016, ref SDS 75 V94O
060529 - Lafayette 5.50 90.1 115 154 081014, ref SDS 74 3E4K
060530 - Lafayette 5.50 92.7 115 138 081013, ref SDS 73 3E4K
060531 - Lafayette 8.25 146.4 180 224 081012, ref SDS 72 3E4K
060532 - Kaiser x 081011, ref SDS 71 UZ7K
060533 - Lafayette 5.50 93.3 116 138 081010, ref SDS 70 3E4K
060534 - Kaiser x 081010, ref SDS 70 UZ7K
060535 - UCSF e 081009, ref SDS 69 V94O
060536 - Lafayette 5.50 92.1 113 137 081006, ref SDS 68 3E4K
060537 - Lafayette 2.75 48.5 110 136 x 081004, ref SDS 67 3E4K
060538 - Lafayette 5.50 98.2 117 136 x 081003, ref SDS 66 3E4K
060539 - UCSF c 081002, ref SDS 65 V94O
060540 - Lafayette 5.50 94.7 115 142 080929, ref SDS 64 3E4K
060541 - Lafayette 8.25 150.4 115 135 080928, ref SDS 64 3E4K
060542 - Kaiser x 080927, ref SDS 63 UZ7K
060543 - Lafayette 5.50 90.2 120 140 x 080926, ref SDS 62 3E4K
060544 - UCSF c 080925, ref SDS 61 V94O
060545 - Lafayette 5.50 92.3 116 138 080923, ref SDS 60 3E4K
060546 - Lafayette 5.50 98.4 112 134 080922, ref SDS 60 3E4K
060547 - Lafayette 5.50 98.2 114 137 080921, ref SDS 60 3E4K
060548 - Lafayette 5.50 101.6 110 133 x 080920, ref SDS 59 3E4K
060549 - Lafayette 5.50 89.3 115 144 x 080919, ref SDS 58 3E4K
060550 - UCSF c 080918, ref SDS 57 V94O
060551 - Lafayette 2.75 46.2 117 139 080916, ref SDS 58 3E4K
060552 - Lafayette 5.50 91.8 117 142 080915, ref SDS 56 3E4K
060553 - Clayton Safeway 3.00 62.4 98 118 080914, ref SDS 55 3E4K
060554 - Lafayette 8.25 129.7 123 147 x 080913, ref SDS 54 3E4K
060555 - Lafayette 5.50 88.4 118 146 x 080912, ref SDS 53 3E4K
060556 - UCSF c 080911, ref SDS 52 V94O
060557 - Lafayette 2.75 46.8 113 140 080909
060558 - Lafayette 5.50 89.2 117 143 080908
060559 - Lafayette 5.50 92.1 115 138 080907
060560 - Lafayette 2.75 45.3 120 144 x 080906, ref SDS 51 3E4K
060561 - Lafayette 2.75 56.8 93 120 x 080905, ref SDS 50 3E4K
060562 - UCSF c 080904, ref SDS 49 V94O
060563 - Lafayette 8.25 140.4 116 131 080903
060564 - Lafayette 5.50 94.9 115 134 080902
060565 - Kaiser x 080830
060566 - Kaiser x 080829
060567 - UCSF c 080828, ref SDS 48 V94O
060568 - Lafayette 5.50 93.6 120 137 080826
060569 - Lafayette 5.50 93.2 117 138 080825
060570 - Lafayette 5.50 93.2 123 136 x 080823
060571 - Lafayette 8.25 142.5 110 131 x 080822, ref SDS 47 3E4K
060572 - UCSF e 080821, ref SDS 46 V94O
060573 - Lafayette 5.50 94.7 115 137 080820
060574 - Lafayette 5.50 94.3 115 135 080819
060575 - Lafayette 8.25 141.7 118 134 080815
060576 - UCSF e 080814, ref SDS 45 V94O
060577 - Lafayette 5.50 93.8 120 136 080813
060578 - Lafayette 5.50 94.4 116 139 080812
060579 - Lafayette 5.50 94.2 119 133 080810
060580 - Lafayette 8.25 143.6 114 132 x 080809, ref SDS 43 3E4K
060581 - Lafayette 8.25 141.1 117 135 x 080808, ref SDS 42 3E4K
060582 - UCSF c 080807, ref SDS 41 V94O
060583 - Lafayette 8.25 143.7 115 132 080805
060584 - Concord 7.00 127.6 105 118 080804
060585 - Lafayette 8.25 143.2 112 134 080802
060586 - Lafayette 5.50 93.4 115 138 080801
060587 - Lafayette 5.50 92.2 118 140 080729
060588 - Lafayette 5.50 92.6 116 137 080728
060589 - Lafayette 8.25 142.6 114 134 080727
060590 - Lafayette 5.50 91.5 120 143 080726
060591 - Lafayette 8.25 140.8 117 135 080725
060592 - Lafayette 5.50 91.8 122 141 080723
060593 - Lafayette 5.50 91.3 120 139 080722
060594 - Lafayette 8.25 143.3 115 133 080720
060595 - Lafayette 5.50 90.7 125 144 080719
060596 - Lafayette 5.50 92.4 123 142 080716
060597 - Lafayette 2.25 46.8 116 137 080715
060598 - Lafayette 8.25 141.8 116 136 080712
060599 - Lafayette 5.50 92.9 116 139 080711
060600 - Lafayette 8.25 143.3 113 137 080704
060601 - Lafayette 5.50 90.2 121 147 080630
060602 - Lafayette 8.25 142.4 116 138 080628
060603 - Lafayette 5.50 91.4 118 138 080625
060604 - Lafayette 2.25 47.9 116 136 080623
060605 - Lafayette 5.50 94.2 112 138 080622
060606 - Lafayette 5.50 94.7 115 133 080621
060607 - Lafayette 2.25 48.3 110 129 080620
060608 - Mt Diablo 7.00 129.4 130 153 080616
060609 - Lafayette 5.50 90.8 120 146 080615
060610 - Lafayette 5.50 91.3 124 144 080614
060611 - Lafayette 5.50 89.7 122 143 080613
060612 - Lafayette 2.76 45.8 120 147 080611
060613 - Lafayette 5.50 90.5 123 145 080609
060614 - Lafayette 5.50 92.7 115 138 080607
060615 - Lafayette 5.50 94.2 118 139 080602
060616 - Lafayette 5.50 96.2 110 202 080507, ref SDS 19 WO8M
060617 -
060618 -
060619 -
060620 -
060621 -
060622 -
0607 -