THE WELCH COMPANY
440 Davis Court #1602
San Francisco, CA 94111-2496
415 781 5700
rodwelch@pacbell.net
S U M M A R Y
DIARY: December 13, 2007 08:00 AM Thursday;
Rod Welch
Millie meeting at UCSF evaluate 12th cycle clinical trial treat IBC.
1...Summary/Objective
2...CT Test 071210 New Findings Right Axillary Enlarged Heart
........Test History No Evidence Distant Metastasis
........Distant Metastasis No Evidence 5 Years Imaging Tests
3...CT Test Results
....5...Findings:
4...Making Sense Possible Conflicting Reports and Terminology
5...Lymphadenopathy Not Identified Right Axillary Lymph Node Increased
6...Right Axillary Lymph Node Increased Not Identified Lymphadenopathy
7...Pretracheal Lymph Node New Findings Conflices Prior Tests
8...Hilar Lymphyadenopathy No Significant Findings
9...Heart Enlarged Mildly No Correlation with Prior Findings
10...Lung Nodules Remain Stable No Evidence of Disease NED for Cancer
........Lung Issues Atelectasis Pneumonia Possible
........Atelectasis Lung Issues Pneumonia Possible
........Pneumonia Possible Atelectasis Lung Issues
........Pulmonary Embolism Associated with CT Findings Atelectasis
ACTION ITEMS..................
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1...Does failure to report enlarged right ventrical for the test on
2...Does finding atelectasis together with failure to report pulmonary
CONTACTS
SUBJECTS
Default Null Subject Account for Blank Record
0403 -
0403 - ..
0404 - Summary/Objective
0405 -
040501 - Follow up ref SDS 45 0000. ref SDS 44 0000.
040502 -
040503 -
040504 -
040505 -
040507 - ..
0406 -
0407 -
0408 - Progress
0409 -
040901 - Doctor Rugo is in Texas with Jackie attending a professional event.
040902 -
040903 -
040904 -
040905 -
040906 -
0410 -
SUBJECTS
CT Test 071210 3 Needle Penetrations Required Medical Mistakes Painf
1003 -
100401 - ..
100402 - CT Test 071210 New Findings Right Axillary Enlarged Heart
100403 -
100404 - Follow up ref SDS 37 4N7K.
100405 -
100406 - Brigid discussed the report with Doctor Rugo which UCSF received from
100407 - Kaiser for the CT scan on 071210, ref SDS 50 IA5N, and requested
100408 - during the meeting at UCSF on 071115. ref SDS 44 EZ48 The test was
100409 - ordered by Jackie from Kaiser on 071203. ref SDS 49 I09N Plans for
100410 - ordering the test were discussed with the doctor at Kaiser on 071116.
100411 - ref SDS 45 OR72 A reminder was submitted to UCSF on 071130.
100412 - ref SDS 48 NL7T
100414 - ..
100415 - Today, Millie asked Brigid during the meeting how UCSF helps patients
100416 - avoid suffering prolonged testing due to difficulty finding a vein for
100417 - IV injections of CT test contrast medium, reported on 071210.
100418 - ref SDS 50 456M
100420 - ..
100421 - Brigid said there is not yet a good solution. Some patients are
100422 - trying to inject contrast medium through a new port catheter designed
100423 - for high pressure injections, but his is still controversial.
100425 - ..
100426 - Test History No Evidence Distant Metastasis
100427 - Distant Metastasis No Evidence 5 Years Imaging Tests
100428 -
100429 - Follow up ref SDS 37 FJ4G, ref SDS 31 LW6M.
100430 -
100431 - Type Date Received Source
100432 - CT 071210 reported on 071213........... ref SDS 0 UG4L
100433 - CT 070930 reported on 071018........... ref SDS 37 VK8L
100434 - CT 070723 reported on 070802........... ref SDS 31 IM6M
100435 - CT 070520 reported on 070524........... ref SDS 30 DA6Q
100436 - CT 070326 reported on 070329........... ref SDS 29 DA6Q
100437 - CT 070131 reported on 070202........... ref SDS 27 1Y8G
100438 - PET/CT 061227 reported on 070102........... ref SDS 22 1Y8G
100439 - CT 060930 reported on 061012........... ref SDS 21 284J
100440 - MRI 060708 reported on 060711........... ref SDS 19 PT4K
100441 - Xray 060623 reported on 060711........... ref SDS 19 WJ6G
100442 - CT 060505 reported on 060523........... ref SDS 17 E355
100443 - PET 060414 reported on 060428........... ref SDS 16 WJ6G
100444 - PET 060120 reported on 060126........... ref SDS 15 WJ6G
100445 - PET/CT 051005 reported on 051007........... ref SDS 14 WJ6G
100446 - CT 050530 reported on 050610........... ref SDS 13 G75L
100447 - CT 050325 reported on 050422........... ref SDS 12 G75L
100448 - CT 041217 reported on 041230........... ref SDS 11 G75L
100449 - CT 041103 reported on 041104........... ref SDS 10 WV7H
100450 - CT 040921 reported on 041005........... ref SDS 9 NL4N
100451 - CT 040710 reported on 040811........... ref SDS 8 H85S
100452 - CT 040410 reported on 040416........... ref SDS 7 LK5L
100453 - CT 040307 reported on 040318........... ref SDS 6 LK5L
100454 - CT 031031 reported on 031205........... ref SDS 5 IG9K
100455 - CT 030626 reported on 030710........... ref SDS 4 AL6N
100456 - CT 030428 reported on 030508........... ref SDS 3 LK5L
100457 - PET 021218 reported on 030109........... ref SDS 2 LK5L
100458 - PET 020529 reported on 020603........... ref SDS 1 0001
100459 -
100460 -
100462 - ..
100463 - CT Test Results
100464 -
100465 -
100466 - 1. CT Scan - chest, abdomen and pelvis performed at Kaiser in
100467 - Walnut Creek on 071210
100469 - ..
100470 - 2. History
100471 -
100472 - 71 yaer old with metastatic breast cncer on clinical trial.
100474 - ..
100475 - Test report continues to err, repeating prior mistakes failing to note
100476 - patient history of pulmonary embolism and enlarged right ventricle
100477 - (core pulmonale), failing to apply standards implemented for Kaiser's
100478 - CT test on 060930, reported on 061012. ref SDS 21 2857
100480 - ..
100481 - CT test 071210 report continues...
100482 -
100483 - 3. Comparison: prior study 070930. [received at UCSF on 071018.
100484 - ref SDS 37 4N7K]
100486 - ..
100487 - 4. Technique:
100488 -
100489 - CT evaluation of the chest abdomen and pelvis was performed
100490 - following the uneventful administration of oral and intravenous
100491 - contrast material.
100492 -
100493 -
1005 -
SUBJECTS
IBC Relapse 4th Progression Disease Lymphadenopathy Increase CT Test
Right Axillary Lymph Node 11 x 11 MM Previously 8 x 7 MM CT Test 071
3804 -
380501 - ..
380502 - 5. Findings:
380503 -
380504 - a. Patient appears to be status post left mastectomy.
380505 -
380507 - ..
380508 - Making Sense Possible Conflicting Reports and Terminology
380509 - Lymphadenopathy Not Identified Right Axillary Lymph Node Increased
380510 - Right Axillary Lymph Node Increased Not Identified Lymphadenopathy
380511 -
380512 -
380513 - b. There is an 11 x 11 mm right axillary lymph node, which
380514 - previously measured 8 x 7 mm. There is no significant
380515 - left-sided lymphadenopathy.
380517 - ..
380518 - This report conflicts with the report for the CT test on 070930, which
380519 - makes no findings of a right axillary lymph node, as shown on 071018.
380520 - ref SDS 37 KK6J
380522 - ..
380523 - During the meeting today, Brigid related discussion with Doctor Rugo
380524 - to make sense of conflicting test reports. They feel the analyst for
380525 - the test on 071210 checked the scans for the prior test on 070930,
380526 - despite no express written findings, and observed conditions which at
380527 - the time either were overlooked, i.e., missed, or were considered too
380528 - small for mentioning in the report for the CT scan on 070930.
380530 - ..
380531 - [On 080118 Kaiser examination reports in Medical Chart
380532 - seems like there is a slow increase in disease
380533 - progression based on gradually increasing CA 15-3 and
380534 - changes in CT scan. ref SDS 53 DR4L
380536 - ..
380537 - [On 080215 CT test on 080212 reports node reported
380538 - today 11 x 11 mm is minimally enlarged, yet says the
380539 - dimensions are 12.7 x 11.3 cm which is 10 times
380540 - greater, ref SDS 54 EO8F; analysis assumes this report
380541 - is an error. ref SDS 54 H65F
380543 - ..
380544 - [On 080215 CT test on 080212 found total of three (3)
380545 - nodes, 300% greater than the test on 071210 reported
380546 - today, though the later test on 080212 says all three
380547 - (3) nodes are present in the current test. ref SDS 54
380548 - H73U Issues of conflicting and erroneous units of
380549 - measure evident for the primary node, cannot be
380550 - determined for the other nodes. ref SDS 54 H73O
380551 -
380552 -
380553 -
3806 -
SUBJECTS
Default Null Subject Account for Blank Record
3903 -
390401 - ..
390402 - Pretracheal Lymph Node New Findings Conflices Prior Tests
390403 -
390404 -
390405 - c. There is a stable 1.6 x 0.7 cm pretracheal lymph node.
390407 - ..
390408 - As well, the report for the CT test on 070930 shows no findings of a
390409 - "stable 1.6 x 0.7 cm pretracheal lymph node." ref SDS 37 KK6J The
390410 - report today therefore conflicts with prior findings.
390411 -
390412 - [On 080215 CT test on 080212 finds stable
390413 - sub-centimeter nodes in right paratracheal. ref SDS 54
390414 - RV70
390416 - ..
390417 - Why are units of measure changed between mm and cm? This invites
390418 - questions of typing errors? 1.6 x 0.7 cm seems like about .25 inches,
390419 - which might be large enough to cause awareness if not discomfort; yet
390420 - the patient has not complained nor noticed a lump in the throat.
390422 - ..
390423 - The record on 060523 reports findings in the CT test on 060505 of less
390424 - than 1 cm lymph nodes in the right paratrachael region. ref SDS 17 4O8P
390425 - There is a note of prior findings of possible esophagitis in the
390426 - report for the PET test on 060120 received on 060126. ref SDS 15 DH4O
390428 - ..
390429 - On 060607 Millie admitted to emergency room for temperature of 104.2;
390430 - xray shows pneumonia, ref SDS 18 PT7S, doctor reports Kaiser's computer
390431 - says Millie has been diagnosed with esophagitis, and asks how
390432 - esophagitis is being treated. ref SDS 18 LO3H Research indicates
390433 - possible correlation between esophagitis and pneumonia. ref SDS 18 I24L
390435 - ..
390436 - The record on 070523 reports disparity in terminology with PET test
390437 - citing "esophagitis" and CT test describing nodes in right
390438 - "paratracheal region" may cause busy doctors and staff to overlook
390439 - alignment in testing that confirms issue for investigation and
390440 - possible treatment, in this case esophagitis. ref SDS 17 Q65O
390442 - ..
390443 - Correlations between "paratrachael" and "pretrachael" and esophagitis,
390444 - if any, are not clear in the record. "Stable pretrachael node"
390445 - reported today, ref SDS 0 SR5P, could be the paratracheal node
390446 - reported on 060523, ref SDS 0 YK6J; or, these may be totally separate
390447 - issues. Curbside research on the Internet seems suggest paratracheal
390448 - and pretracheal are either the same thing or closely related, but this
390449 - could be completely incorrect.
390451 - ..
390452 - [On 080219 report for CT test on 080212 says node in
390453 - right axilla measures 12.7 x 11.3 cm, which is a 10
390454 - fold increase, indicating typing error or misreading.
390455 - ref SDS 55 1K8T
390456 -
390457 -
390458 -
3905 -
SUBJECTS
Default Null Subject Account for Blank Record
4003 -
400401 - ..
400402 - Hilar Lymphyadenopathy No Significant Findings
400403 -
400404 -
400405 - d. There is no significant hilar lymphadenopathy.
400406 -
400407 -
400408 -
4005 -
SUBJECTS
Default Null Subject Account for Blank Record
4103 -
410401 - ..
410402 - Heart Enlarged Mildly No Correlation with Prior Findings
410403 -
410404 -
410405 - CT test 071210 report Findings continue...
410406 -
410407 - e. The heart appears mildly enlarged.
410409 - ..
410410 - There is no comparison with prior findings of pulmonary embolism from
410411 - test on 060930, reviewed on 061012, ref SDS 21 294Q; and similarly no
410412 - comparison today with enlarged right ventricle (cor pulmonale).
410413 - ref SDS 21 7E5L
410414 -
410415 - [On 080118 meeting with primary care physician at Kaiser
410416 - reviewed CT test findings of mildly enlarged heart; doctor
410417 - feels no referral to cardio pulmonary specialist required
410418 - to investigate until treatable symptoms become evident.
410419 - ref SDS 53 HP9T
410421 - ..
410422 - [On 080215 CT test for 080212 repeats errors in the report
410423 - today, and further does not list patient history of
410424 - enlarged heart reported today. ref SDS 54 IX4F
410426 - ..
410427 - [On 080507 Millie reports spike in heart beat (pulse) while
410428 - laying down in bed; case study shows occassional spike in
410429 - pulse reported by heart monitor during exercise, evaluated
410430 - previously as defective equipment. ref SDS 57 CK4K
410432 - ..
410433 - [On 080723 CT test on 080718 reports heart appears normal
410434 - size. ref SDS 58 UR4S
410436 - ..
410437 - [On 081012 pulse elevated to maximum of 224, and remained
410438 - high for most of 2 laps, then returned to normal on the 3rd
410439 - lap. ref SDS 59 FL7M
410441 - ..
410442 - [On 081105 Millie notified that primary care physician
410443 - orders Muga test for heart damage prior to starting
410444 - sunitinib clinical study that has some heart related side
410445 - effects. ref SDS 60 WO72
410447 - ..
410448 - The analyst does not comment on possible correlations and implications
410449 - finding mildly enlarged heart with also finding atelectasis.
410450 - ref SDS 0 SR66
410452 - ..
410453 - Does failure to report enlarged right ventrical for the test on
410454 - 071210, establish that the condition reported in the test on 060930
410455 - has been resolved?
410456 -
410457 -
410459 - ..
410460 - Lung Nodules Remain Stable No Evidence of Disease NED for Cancer
410461 -
410462 -
410463 - CT test 071210 report continues...
410464 -
410465 - f. There is some stable interstial/fibrotic change within the
410466 - left lung apex. There is a stable ill defined 4 mm nodular
410467 - density within the left lung base. There is also a stable
410468 - 3 mm ill defined nodular density within the left lung base
410469 - on image #51.
410471 - ..
410472 - Representation of "...stable...change..." within the left lung apex is
410473 - unclear.
410475 - ..
410476 - Stable nodules in the lungs were cited by the primary care physician
410477 - at Kaiser in a letter on 070117 to explain the medical chart reporting
410478 - lung cancer. ref SDS 25 TS8G
410479 -
410480 -
410482 - ..
410483 - Lung Issues Atelectasis Pneumonia Possible
410484 - Atelectasis Lung Issues Pneumonia Possible
410485 - Pneumonia Possible Atelectasis Lung Issues
410486 - Pulmonary Embolism Associated with CT Findings Atelectasis
410487 -
410488 -
410489 - CT test 071210 report continues...
410490 -
410491 - g. There is some interstitial prominence and ground-glass
410492 - opacity within the right lower lobe medially, which is
410493 - slightly increased. This appearance may be partially due
410494 - to atelectasis. Pneumonia cannot be excluded.
410495 -
410496 - [On 080507 Millie reports spike in heart beat (pulse)
410497 - while laying down in bed; case study shows occassional
410498 - spike in pulse reported by heart monitor during
410499 - exercise, evaluated previously as defective equipment.
410500 - ref SDS 57 CK4K
410502 - ..
410503 - Finding "some interstitial prominence within the right lobe medially
410504 - is slightly increased," appears conflicting with the prior test on
410505 - 070930, since review on 071018 shows no findings of interstitial
410506 - disease in the lungs, noting simply the "lungs are unchanged."
410507 - ref SDS 37 KK6J The prior CT test on 070723 was reviewed at UCSF on
410508 - 070802 and reported only: "No new pulmonary nodules identified. Left
410509 - apical groundglass opacities with associated septal thickening is
410510 - stable in appearance and is likely due to post inflammatory scarring."
410511 - ref SDS 31 OX4O The next earlier test on 070520 was reviewed on
410512 - 070524 and affirmatively reported "no interstitial disease."
410513 - ref SDS 30 SP3F If there was none before, how can some be increased
410514 - now?
410516 - ..
410517 - Millie has patient history of pneumonia, diagnosed on 060607.
410518 - ref SDS 18 PT7S There is no prior record reporting atelectasis.
410520 - ..
410521 - Patient history of pulmonary embolism reported on 060722 shows
410522 - difficulties with diagnosis. ref SDS 20 6G6O
410524 - ..
410525 - Does finding atelectasis together with failure to report pulmonary
410526 - embolism for the test on 071210, establish that the condition reported
410527 - in the test on 060930 has been resolved? Does the report today show
410528 - that Kaiser performed the work on this test which was ordered by the
410529 - doctor and not performed for the prior tests?
410530 -
410531 - "Atelectasis" is explained on the Internet at...
410532 -
410533 - Mediline Plus
410534 - Medical Encyclopedia
410536 - ..
410537 - http://www.nlm.nih.gov/medlineplus/ency/article/000065.htm
410539 - ..
410540 - Atelectasis is the collapse of part or all of a lung. It
410541 - is caused by a blockage of the air passages (bronchus or
410542 - bronchioles) or by pressure on the lung
410544 - ..
410545 - Atelectasis seems associated with pulmonary embolism, either a cause,
410546 - or caused by, and can be mistaken for PE...
410547 -
410548 - Emedicine
410549 - Pulmonary Embolism
410550 - Last updated: 070607
410552 - ..
410553 - http://www.emedicine.com/emerg/topic490.htm
410555 - ..
410556 - Imaging Studies:
410557 -
410558 - Over time, an initially normal CXR often begins to show
410559 - atelectasis, which may progress to cause a small
410560 - pleural effusion and an elevated hemidiaphragm.
410561 -
410563 - ..
410564 - Emedicine
410565 - Atelectasis
410566 - Last updated: 060614
410567 -
410568 - http://www.emedicine.com/med/topic180.htm
410570 - ..
410571 - Platelike atelectasis
410573 - ..
410574 - Also called discoid or subsegmental atelectasis, this type
410575 - is seen most commonly on chest radiographs. Platelike
410576 - atelectasis probably occurs because of obstruction of a
410577 - small bronchus and is observed in states of
410578 - hypoventilation, pulmonary embolism, or lower respiratory
410579 - tract infection. Small areas of atelectasis occur because
410580 - of inadequate regional ventilation and abnormalities in
410581 - surfactant formation from hypoxia, ischemia, hyperoxia, and
410582 - exposure to various toxins. A mild-to-severe gas exchange
410583 - abnormality may occur because of ventilation-perfusion
410584 - mismatch and intrapulmonary shunt.
410585 -
410587 - ..
410588 - Karger
410589 - Respiration
410590 - International Journal of Thoracic Medicine
410592 - ..
410593 - Vol 70, No., 5, 2003
410594 -
410595 - http://content.karger.com/ProdukteDB/produkte.asp?Aktion=ShowFulltext&ArtikelNr=74195&Ausgabe=229717&ProduktNr=224278#abstract
410597 - ..
410598 - Transthoracic Ultrasound of Lung and Pleura in the
410599 - Diagnosis of Pulmonary Embolism: A Novel Non-Invasive
410600 - Bedside Approach
410601 - Angelika Reissig, Claus Kroegel
410603 - ..
410604 - ...in PE... the cessation of pulmonary arterial flow in the
410605 - areas distal to the perfusion stoppage may result in
410606 - atelectasis due to a rapid breakdown of the surfactant
410607 - lining the inner surface of the airspace.
410609 - ..
410610 - CT test 071210 report continues...
410611 -
410612 - h. There is a stable 1.7 cm cyst within the liver dome. The
410613 - remainder of the liver, adrenal glands, pancreas, and
410614 - gallbladder are unremarkable. There are calcific foci
410615 - within the spleen, compatible with calcified granulomata.
410617 - ..
410618 - i. There is a too small to characterize low attentuation
410619 - lesion within each kidney, which is unchanged. Thre is no
410620 - lymphadenopathyor ascities within the abdomen or pelvis.
410621 - No evidence of bowel obstruction. Sigmoid diverticular are
410622 - again noted. The unary bladder is underdistended.
410624 - ..
410625 - j. Degenerative changes are noted within the lower lumbar
410626 - spine.
410628 - ..
410629 - 6. Impression
410630 -
410631 - 1. Status post left mastectomy. Interval enlargement of a
410632 - right axilary lymph node. ref SDS 0 SR5P
410633 -
410634 - 2. Mild ground-glass opacity and interstitial prominence
410635 - within the right lower lobe medially, which is increased
410636 - from the prior study. ref SDS 0 SR66
410638 - ..
410639 - 3. Stable evaluation of the abdomen and pelvis.
410640 -
410642 - ..
410643 - Brigid reported discussions with Doctor Rugo who is traveling today
410644 - for a professional event in Texas.
410646 - ..
410647 - Brigid related the doctor's comments noting increased detail in
410648 - findings of the report today for the test on 071210, compared to
410649 - minimal analysis in the report for the CT test on 070930, which was
410650 - reviewed at UCSF on 071018. ref SDS 37 4N7K
410652 - ..
410653 - The report for the test on 071210 seems confusing because comparison
410654 - is presented for the right axillary with the prior test on 070930,
410655 - which actually reports "...no axillary adenopathy" ref SDS 37 KK6J
410656 - The doctor feels the analyst in this case may have observed findings
410657 - for the test on 071210, and then examined the prior scan on 070930 and
410658 - noted something was missed in the prior report, or not reported
410659 - because 8 x 7 mm is below 1 cm commonly used for reporting.
410661 - ..
410662 - The doctor feels the report today does not justify consideration for
410663 - changing treatment, for example by adding carboplatin at this time,
410664 - and pending CA 15-3 cancer report for the blood test taken this
410665 - morning. This will be available next week, per below.
410667 - ..
410668 - Brigid made a careful examination particularly of the right axillary
410669 - and found no indications of swelling that might suggest adenopathy.
410671 - ..
410672 - Examination showed possibly expanding or more intense IBC area in the
410673 - stomach and abdomen area.
410675 - ..
410676 - Since Jackie is traveling with the doctor to the conference in San
410677 - Antonio, Brigid asked Megan to take a photograph of the IBC on the
410678 - stomache.
410680 - ..
410681 - The rest of the IBC sites appear stable, including the right breast
410682 - and the left arm.
410684 - ..
410685 - Swelling of the left arm from cellulitis that compounds lymphedema has
410686 - completely subsided, especially below the elbow and the the hand.
410688 - ..
410689 - Brigid commented on how well Millie looks.
410691 - ..
410692 - Discussed how to exercise Millie's left arm without causing stress
410693 - that induces cellulitis recurrence.
410695 - ..
410696 - Brigid said this can only be done through trial and error.
410697 -
410698 - [On 071214 Millie suffered mild relapse Cellulitis; treated at
410699 - home with Keflex on hand. ref SDS 52 SR8R
410701 - ..
410702 - Millie went into the Influsion Clinic at 0750. Diane was not in this
410703 - morning, but there were two nurses who were able to draw blood for the
410704 - test based on the lab slip, which Jackie submitted a few days ago.
410706 - ..
410707 - During the meeting, OA 0840, Brigid noticed results of the blood test
410708 - this morning were already posted to the computer.
410710 - ..
410711 - WBC was low for the first time in 4 or 5 months. This caused NEUTS to
410712 - fall to 1.49, which is barely below 1.5 standard for safe treatment.
410713 - Brigid approved treatment today consistent with prior practice
410714 - approving treatment with NEUTS as low as 1.23, reported on 070301.
410715 - ref SDS 28 P560
410717 - ..
410718 - Magnesium was slightly low. ref SDS 51 A14L Catherine contacted
410719 - Brigid, who prescribed magnesium treatment. Catherine gave this
410720 - treatment with IV injection during the rest period after treatment
410721 - with cetuximab.
410722 -
410723 - [On 080404 UCSF reports difficulty communicating quickly and
410724 - accurately to coordinate referral work with Kaiser ordering
410725 - Magnesium medication for Millie. ref SDS 56 OP69
410726 -
410727 -
410728 -
410729 -
410730 -
410731 -
410732 -
410733 -
410734 -
410735 -
4108 -