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S U M M A R Y


DIARY: June 9, 2005 04:10 PM Thursday; Rod Welch

Study shows exercise aids recovery from breast cancer.

1...Summary/Objective


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Exercise Stimulates Cells to Help Repair Some Damage to the Immune S
Exercise Strength Aids Recovery from Breast Cancer Reuters Article
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0905 -
0905 -    ..
0906 - Summary/Objective
0907 -
090701 - Follow up ref SDS 4 0000, ref SDS 3 NN6N.
090702 -
090703 - Evidence today that Millie's history of vigorous exercise seems to
090704 - contribute to her ability to beat the odds in fighting off repeated
090705 - waves of relapse.
090706 -
090707 -
090708 -
090709 -
090710 -
090712 -  ..
0908 -
0909 -
0910 - Progress
0911 -
091101 - Article published by Reuters on the Internet reports study that found
091102 - exercise aids recovery from breast cancer. ref OF 1 0001
091103 -
091104 -    1.  WASHINGTON (Reuters) - Exercise, already shown to help prevent
091105 -        breast cancer, can also help women recover from surgery and
091106 -        other breast cancer treatments, U.S. researchers reported on
091107 -        Thursday. ref OF 1 F019
091109 -         ..
091110 -    2.  While the instinct may be to lie low and rest up, in fact it is
091111 -        better to get up and move, even doing strength training, the
091112 -        researchers found. ref OF 1 006K
091114 -         ..
091115 -    3.  Breast cancer patients who exercised with a trainer after
091116 -        surgery, chemotherapy or radiation treatment felt better and
091117 -        stronger, and their immune systems appeared healthier, than
091118 -        women who rested, according to the study released at a
091119 -        Department of Defense breast cancer meeting in Philadelphia.
091120 -        ref OF 1 Q95N
091122 -         ..
091123 -    4.  "We have some evidence that exercise can help stimulate some of
091124 -        the cells in the immune system and help repair some of the
091125 -        damage done by chemotherapy," study leader Andrea Mastro, a
091126 -        professor of microbiology and cell biology at Pennsylvania
091127 -        State University, said in a telephone interview. ref OF 1 008K
091129 -  ..
091130 - This fits Kaisers recommendations on 030606, ref SDS 1 LZ3L, and more
091131 - recently on 041019 by Doctor Guardino at Stanford. ref SDS 3 NN6N  In
091132 - particular, exercise enables older patient's to sustain chemotherapy
091133 - treatment long enough to recover, rather than succumb to cumulative
091134 - damage to the immune system. ref SDS 1 XR7I  At that time on 030306,
091135 - the doctor cited Millie's high level of fitness resists cancer,
091136 - ref SDS 1 JP7G, and noted Millie fitness tolerates aggressive
091137 - chemotherapy treatments. ref SDS 1 NE57  On 031205 the doctor
091138 - commended Millie's fitness from vigorous exercise, which contributes
091139 - to tolerating aggressive treatment. ref SDS 2 GW8F
091140 -
091141 -            [On 050613 Millie feeling strong durng treatment cycles;
091142 -            hiked 3 miles. ref SDS 5 QJ7M
091144 -             ..
091145 -            [On 050712 Ron Sr suggested researching natural remedies to
091146 -            heal cancer; found article on enzyme therapy recommending
091147 -            build up body energy and strengthen the immune system.
091148 -            ref SDS 6 1479
091150 -             ..
091151 -            [On 050729 accumulating effects of chemotherapy treatment
091152 -            reducing tolerance for further treatment. ref SDS 7 DS5J
091154 -             ..
091155 -            [On 070607 Millie Cellulitis recurrence from exercise to
091156 -            maintain fitness and strengthen immune system to resist
091157 -            cancer. ref SDS 8 6A7J
091159 -             ..
091160 -            [On 080501 exercise and fitness increase after starting
091161 -            Carboplatin chemotherapy on 2nd arm of clincial study
091162 -            Millie treated on referral at UCSF. ref SDS 9 2G4G
091163 -
091165 -  ..
091166 - Article continues...
091167 -
091168 -    5.  "This wouldn't be specific to breast cancer patients," she
091169 -        added. ref OF 1 F66N
091171 -         ..
091172 -    6.  Mastro's findings go against the common wisdom of both women
091173 -        and their doctors. ref OF 1 PPTQ
091175 -         ..
091176 -    7.  "It interested me that some of the women we approached said,
091177 -        'Oh I don't know -- my doctor said I should just take it easy
091178 -        for a while,"' Mastro said. ref OF 1 004L
091180 -         ..
091181 -    8.  For their study, Mastro's team studied female breast cancer
091182 -        patients aged between 29 and 71, among them 28 who exercised
091183 -        regularly with a personal trainer and 21 who continued their
091184 -        normal, sedentary routines. ref OF 1 PPTX
091186 -         ..
091187 -    9.  "We wanted to include some resistance exercise because we had
091188 -        some evidence from healthy young women that resistance exercise
091189 -        could stimulate the immune system but we didn't want these
091190 -        women to have to go to a gym," Mastro said. ref OF 1 PPUS
091192 -         ..
091193 -   10.  The women did warmups and stretches, 15 to 20 minutes of
091194 -        strength training with exercise bands, and 15 to 20 minutes of
091195 -        aerobic exercise such as walking on a treadmill or a using a
091196 -        stationary bike. ref OF 1 006N
091198 -         ..
091199 -   11.  NORMAL ROUTINES
091200 -
091201 -        The other women continued their normal routines, which may have
091202 -        included a little walking but usually not even that.
091203 -        ref OF 1 PPVR
091205 -         ..
091206 -   12.  "Most of the women had the same chemotherapy followed by
091207 -        radiation therapy, and most reported doing little if any
091208 -        regular exercise before diagnosis," Mastro said. ref OF 1 00FN
091210 -         ..
091211 -   13.  After three months the women filled out questionnaires about
091212 -        their health and how they felt. ref OF 1 F64H
091214 -         ..
091215 -   14.  "They (exercisers) showed increased quality of life," she said.
091216 -        "Their social well being was higher and they were less
091217 -        fatigued." ref OF 1 F64M
091219 -         ..
091220 -   15.  The exercisers had an overall average quality of life test
091221 -        score of 101.4, compared to 93.9 for the non-exercisers.
091222 -        ref OF 1 00HO
091223 -
091224 -            [On 080501 exercise and fitness increase after starting
091225 -            Carboplatin chemotherapy on 2nd arm of clincial study
091226 -            Millie treated on referral at UCSF. ref SDS 9 FW5J
091228 -         ..
091229 -   16.  Cancer patients often show raised levels of compounds such as
091230 -        interleukin 6 or gamma interferon, which are inflammatory
091231 -        agents, in their blood.  The exercisers had a quicker decline
091232 -        in the compounds, Mastro said. ref OF 1 F65K
091234 -         ..
091235 -   17.  Immune system cells called CD4 helper T-cells, which are
091236 -        damaged by chemotherapy, started to divide faster in the
091237 -        exerciser group, Mastro added. ref OF 1 F65Q
091239 -  ..
091240 - This fits the primary care physician's recommendations on 030606.
091241 - ref SDS 1 LZ3L
091242 -
091243 -            [On 081018 report in seminar that recent research indicates
091244 -            exercise improves recovery from cancer and resists
091245 -            recurrence by 60%. ref SDS 10 IT68
091247 -  ..
091248 - Article continues...
091249 -
091250 -   18.  Mastro's study fits in with several others, including a report
091251 -        published last month in the Journal of the American Medical
091252 -        Association by Harvard Medical School researchers who studied
091253 -        18 years' worth of data from 3,000 breast cancer patients.
091254 -        ref OF 1 00BP
091256 -         ..
091257 -   19.  The U.S.  Army Medical Research and Materiel Command's breast
091258 -        cancer research program has received more than $1.8 billion to
091259 -        date from Congress for research. ref OF 1 F66Q
091261 -         ..
091262 -   20.  Worldwide, nearly 1.2 million women and men will be diagnosed
091263 -        with breast cancer this year.  In the United States, breast
091264 -        cancer will kill 40,000 people this year. ref OF 1 00DP
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