CONTACTS 

SUBJECTS
Meeting Doctor Johnson Planning Start Treatments

0403 -
0403 -    ..
0404 - Summary/Objective
0405 -
040501 - Follow up ref SDS 11 0000. ref SDS 9 0000.
040502 -
040503 -
040504 -
040505 -
040506 -
040507 -
040509 -  ..
0406 -
0407 -
0408 - Progress
0409 -
040901 - Agenda...
040902 -
040903 -          1.  CA 15-3
040904 -
040905 -              CA 15-3 began to drop from 95 reported on 050308,
040906 -              ref SDS 14 0001, to 88, as expected, during the meeting
040907 -              on 050212. ref SDS 11 ZF7F  Will continue to monitor for
040908 -              trend establishing favorable response to treatment.
040910 -               ..
040911 -          2.  CT Test results
040912 -
040913 -              New CT test scheduled for 050325.
040914 -
040916 -               ..
040917 -          3.  Breast examination
040918 -
040919 -              Much of the breast is improving, especially the lower
040920 -              half.  Coloration and softness seem more normal today,
040921 -              and the sore from the punch biopsy taken on 040419 has
040922 -              nearly healed, indicating response to treatment that
040923 -              aligns with falling CA 15-3 tests.
040925 -               ..
040926 -              AC treatment was interrupted on 050212 by hospital stay
040927 -              of 4 days due to infection from cat bite. ref SDS 12 0001
040928 -              This lowered WBC that affects immune system, so doctor
040929 -              skipped a week of treatment, reported on 050214.
040930 -              ref SDS 13 02BB  Skipping treatment reduces concentration
040931 -              which may have caused cancer to increase.
040933 -               ..
040934 -              The upper left area of the breast has new bumps, and
040935 -              sores, and IBC coloration is stronger in this area, and
040936 -              has begun to spread upward toward the neck.  This is
040937 -              similar to the condition reported on 041202 that caused
040938 -              Millie to get treatment at the emergency room.
040939 -              ref SDS 3 0001  In that case, it turned out that
040940 -              increased inflammation and temperature were expected side
040941 -              effects, ref SDS 3 RC92, which had not been disclosed by
040942 -              the doctor at the time medication was prescribed two (2)
040943 -              days earlier to treat the wound from the punch biopsy
040944 -              taken a year earlier on 040419, which had not healed.
040945 -              Today, the doctor feels these new more severe conditions
040946 -              may indicate the breast has pockets of cancer that are
040947 -              resistant to AC chemotherapy treatments, which have been
040948 -              administered unevenly due to low blood counts.
040950 -               ..
040951 -              The doctor commented these pockets of resistance to
040952 -              chemotherapy may be treatable with surgery.
040953 -
040954 -                  [On 050329 switched treatment to Taxotere and
040955 -                  capecitabine (Xeloda), because disease progressing
040956 -                  during treatments with AC. ref SDS 16 887S
040958 -                   ..
040959 -                  [On 050502 visual improvement sores and inflamation
040960 -                  are receding, ref SDS 17 EO5J
040962 -                   ..
040963 -                  [On 050510 further improvement inflammation (redness)
040964 -                  seems entirely gone, and softness has returned to the
040965 -                  breast. ref SDS 18 EO5J
040967 -                   ..
040968 -                  [On 050520 dramatic improvement after 2 cycles of
040969 -                  treatment with Taxotere and Xeloda. ref SDS 19 R19I
040971 -               ..
040972 -              During the meeting, Doctor Johnson called Doctor
040973 -              Riley-Paull and left a voice mail message asking the
040974 -              doctor to examine Millie for surgery, because the breast
040975 -              may be resistant to full recovery with drugs.
040976 -
040977 -                  [On 050324 meeting with Doctor Riley-Paull who found
040978 -                  conditions that make surgery very high risk, and so
040979 -                  not recommended until recovery from IBC is
040980 -                  accomplished with chemotherapy. ref SDS 15 0001
040981 -
040983 -               ..
040984 -          4.  Treatment plan...
040985 -
040986 -              Doctor Johnson related the following treatment plan...
040987 -
040988 -              a.  AC chemotherapy treatment scheduled for 050318, based
040989 -                  on demonstration of response where CA 15-3 has
040990 -                  finally begun to fall, and much of the breast appears
040991 -                  less inflammed, punch biopsy nearly healed.
040993 -                   ..
040994 -              b.  Muga test on 050328 to evaluate impact of AC
040995 -                  chemotherapy on heart and assess whether this
040996 -                  treatment can be continued.
040998 -                   ..
040999 -              c.  Visit Doctor Johnson in 2 weeks, on 050329 to
041000 -                  evaluate tests and report from Doctor Riley-Paull
041001 -                  about continuing with AC chemotherapy, changing to a
041002 -                  new protocol, and/or surgery.
041003 -
041004 -
041006 -  ..
0411 -
0412 -
0413 - Discussion
0414 -
041401 - Agenda for Work Plan After 2 Treatments of AC
041402 -
041403 - Follow up ref SDS 11 SM6M, ref SDS 8 SM6M.
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0415 -